Antimicrobial resistance profiles of Escherichia coli derived from an integrated agroforestry-livestock system in Deli Serdang Regency, Indonesia
Background and Aim: Antimicrobial resistance (AMR) has become a significant global concern. Epidemiological data do not provide a robust description of the potential risks associated with AMR in the integrated agroforestry-livestock systems in Indonesia. Thus, the present study investigated the phen...
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| Format: | Article |
| Language: | English |
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Veterinary World
2024-03-01
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| Series: | Veterinary World |
| Subjects: | |
| Online Access: | https://www.veterinaryworld.org/Vol.17/March-2024/21.pdf |
| _version_ | 1797215824205840384 |
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| author | Rita Rosmala Dewi Arif Nuryawan Saleh Mohammed Jajere Juli Mutiara Sihombing Ika Julianti Tambunan |
| author_facet | Rita Rosmala Dewi Arif Nuryawan Saleh Mohammed Jajere Juli Mutiara Sihombing Ika Julianti Tambunan |
| author_sort | Rita Rosmala Dewi |
| collection | DOAJ |
| description | Background and Aim: Antimicrobial resistance (AMR) has become a significant global concern. Epidemiological data do not provide a robust description of the potential risks associated with AMR in the integrated agroforestry-livestock systems in Indonesia. Thus, the present study investigated the phenotypic and multidrug resistance (MDR) profiles of Escherichia coli strains isolated from the feces of livestock raised in the agro-silvopastoral system in Deli Serdang Regency, North Sumatra Province.
Materials and Methods: A standard microbiological culture procedure was followed to isolate the organism and test antibiotic susceptibility using the Kirby-Bauer disk diffusion protocol. Furthermore, the multiple antibiotic resistance index was determined. Univariate analysis was conducted to identify the risk factors associated with AMR.
Results: The vast majority (77.5%) of livestock farmers were aged >30 years. All farmers were men and had no higher education (100% of them). The majority of the animal species managed were cattle and goats (37.5% each) and the livestock grazing pasture system (67.5%). In addition, the majority of farmers reported high antimicrobial use on their farms (87.5%). Of the samples (n = 142) analyzed, n = 70 were positive, with an overall prevalence of 44.4%. The species-specific prevalences of E. coli were 32.5%, 47.8%, and 50% in buffalo, goat, and cattle, respectively. Ampicillin and tetracyclines exhibited high resistance levels among the studied animal species. A relatively lower MDR for E. coli was associated with grazing on the pasture.
Conclusion: The findings from the current study provide baseline epidemiological information for future robust studies aimed at elucidating the drivers and patterns of AMR in agro-silvopastoral systems in the study area or elsewhere. |
| first_indexed | 2024-04-24T11:36:12Z |
| format | Article |
| id | doaj.art-5c75d084191e4c6d973a609d142e545c |
| institution | Directory Open Access Journal |
| issn | 0972-8988 2231-0916 |
| language | English |
| last_indexed | 2024-04-24T11:36:12Z |
| publishDate | 2024-03-01 |
| publisher | Veterinary World |
| record_format | Article |
| series | Veterinary World |
| spelling | doaj.art-5c75d084191e4c6d973a609d142e545c2024-04-10T05:04:15ZengVeterinary WorldVeterinary World0972-89882231-09162024-03-0117369069910.14202/vetworld.2024.690-699Antimicrobial resistance profiles of Escherichia coli derived from an integrated agroforestry-livestock system in Deli Serdang Regency, IndonesiaRita Rosmala Dewi0https://orcid.org/0000-0002-4294-5729Arif Nuryawan1https://orcid.org/0000-0002-4525-6937Saleh Mohammed Jajere2https://orcid.org/0000-0001-6977-9815Juli Mutiara Sihombing3Ika Julianti Tambunan4Department of Animal Husbandry, Faculty of Science and Technology, Universitas Tjut Nyak Dhien, Medan, Indonesia.Department of Forestry, Faculty of Forestry, Universitas Sumatera Utara, Medan, Indonesia.Department of Veterinary Public Health and Preventive Medicine, Faculty of Veterinary Medicine, University of Maiduguri, Maiduguri, Borno State, Nigeria.Department of Animal Husbandry, Faculty of Science and Technology, Universitas Tjut Nyak Dhien, Medan, Indonesia.Department of Pharmacy, Faculty of Pharmacy, Universitas Tjut Nyak Dhien, Medan, Indonesia.Background and Aim: Antimicrobial resistance (AMR) has become a significant global concern. Epidemiological data do not provide a robust description of the potential risks associated with AMR in the integrated agroforestry-livestock systems in Indonesia. Thus, the present study investigated the phenotypic and multidrug resistance (MDR) profiles of Escherichia coli strains isolated from the feces of livestock raised in the agro-silvopastoral system in Deli Serdang Regency, North Sumatra Province. Materials and Methods: A standard microbiological culture procedure was followed to isolate the organism and test antibiotic susceptibility using the Kirby-Bauer disk diffusion protocol. Furthermore, the multiple antibiotic resistance index was determined. Univariate analysis was conducted to identify the risk factors associated with AMR. Results: The vast majority (77.5%) of livestock farmers were aged >30 years. All farmers were men and had no higher education (100% of them). The majority of the animal species managed were cattle and goats (37.5% each) and the livestock grazing pasture system (67.5%). In addition, the majority of farmers reported high antimicrobial use on their farms (87.5%). Of the samples (n = 142) analyzed, n = 70 were positive, with an overall prevalence of 44.4%. The species-specific prevalences of E. coli were 32.5%, 47.8%, and 50% in buffalo, goat, and cattle, respectively. Ampicillin and tetracyclines exhibited high resistance levels among the studied animal species. A relatively lower MDR for E. coli was associated with grazing on the pasture. Conclusion: The findings from the current study provide baseline epidemiological information for future robust studies aimed at elucidating the drivers and patterns of AMR in agro-silvopastoral systems in the study area or elsewhere.https://www.veterinaryworld.org/Vol.17/March-2024/21.pdfagro-silvopastoralantimicrobial resistanceescherichia coliindonesialivestockmultidrug resistance |
| spellingShingle | Rita Rosmala Dewi Arif Nuryawan Saleh Mohammed Jajere Juli Mutiara Sihombing Ika Julianti Tambunan Antimicrobial resistance profiles of Escherichia coli derived from an integrated agroforestry-livestock system in Deli Serdang Regency, Indonesia Veterinary World agro-silvopastoral antimicrobial resistance escherichia coli indonesia livestock multidrug resistance |
| title | Antimicrobial resistance profiles of Escherichia coli derived from an integrated agroforestry-livestock system in Deli Serdang Regency, Indonesia |
| title_full | Antimicrobial resistance profiles of Escherichia coli derived from an integrated agroforestry-livestock system in Deli Serdang Regency, Indonesia |
| title_fullStr | Antimicrobial resistance profiles of Escherichia coli derived from an integrated agroforestry-livestock system in Deli Serdang Regency, Indonesia |
| title_full_unstemmed | Antimicrobial resistance profiles of Escherichia coli derived from an integrated agroforestry-livestock system in Deli Serdang Regency, Indonesia |
| title_short | Antimicrobial resistance profiles of Escherichia coli derived from an integrated agroforestry-livestock system in Deli Serdang Regency, Indonesia |
| title_sort | antimicrobial resistance profiles of escherichia coli derived from an integrated agroforestry livestock system in deli serdang regency indonesia |
| topic | agro-silvopastoral antimicrobial resistance escherichia coli indonesia livestock multidrug resistance |
| url | https://www.veterinaryworld.org/Vol.17/March-2024/21.pdf |
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