Ischemic stroke causes Parkinson’s disease-like pathology and symptoms in transgenic mice overexpressing alpha-synuclein

Ischemic stroke causes Parkinson’s disease-like pathology and symptoms in transgenic mice overexpressing alpha-synuclein

Abstract The etiology of Parkinson’s disease is poorly understood and is most commonly associated with advancing age, genetic predisposition, or environmental toxins. Epidemiological findings suggest that patients have a higher risk of developing Parkinson’s disease after ischemic stroke, but this p...

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Bibliographic Details
Main Authors: Stephanie Lohmann, Jessica Grigoletto, Maria Eugenia Bernis, Verena Pesch, Liang Ma, Sara Reithofer, Gültekin Tamgüney
Format: Article
Language:English
Published: BMC 2022-02-01
Series:Acta Neuropathologica Communications
Subjects:
Ischemic stroke
Ischemia
Stroke
Parkinson’s disease
Synucleinopathy
Alpha-synuclein
Online Access:https://doi.org/10.1186/s40478-022-01327-6

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