Ginseng for Erectile Dysfunction: A Cochrane Systematic Review
The objectives of this study were to assess the effects of ginseng on erectile dysfunction. We searched multiple electronic databases from their inceptions to 30 January 2021 without restrictions by language. We included randomized or quasirandomized controlled trials that evaluated the use of any...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Korean Society for Sexual Medicine and Andrology
2022-04-01
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| Series: | The World Journal of Men's Health |
| Subjects: |
| _version_ | 1818354858452844544 |
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| author | Hye Won Lee Myeong Soo Lee Tae-Hun Kim Terje Alraek Chris Zaslawski Jong Wook Kim Du Geon Moon |
| author_facet | Hye Won Lee Myeong Soo Lee Tae-Hun Kim Terje Alraek Chris Zaslawski Jong Wook Kim Du Geon Moon |
| author_sort | Hye Won Lee |
| collection | DOAJ |
| description | The objectives of this study were to assess the effects of ginseng on erectile dysfunction. We searched multiple electronic
databases from their inceptions to 30 January 2021 without restrictions by language. We included randomized or quasirandomized
controlled trials that evaluated the use of any type of ginseng as a treatment for erectile dysfunction compared
to placebo or conventional treatment. The authors independently screened the literature, extracted data, assessed risk of bias,
and rated the certainty of evidence (CoE) according to the GRADE approach. We included nine studies, and all compared
ginseng to placebo. Ginseng appears to have a trivial effect on erectile dysfunction when compared to placebo based on the
Erectile Function Domain of the International Index of Erectile Function (IIEF)-15 instrument (mean difference [MD] 3.52,
95% confidence interval [CI] 1.79 to 5.25; I²=0%; 3 studies; low CoE). Ginseng may have little to no effect on adverse events
compared to placebo (risk ratio [RR] 1.45, 95% CI 0.69 to 3.03; I²=0%; 7 studies; low CoE). While ginseng may improve
men's self-reported ability to have intercourse (RR 2.55, 95% CI 1.76 to 3.69; I²=23%; 6 studies; low CoE), it may have a trivial
effect on men's satisfaction with intercourse based on the Intercourse Satisfaction Domain of the IIEF-15 (MD 1.19, 95%
CI 0.41 to 1.97; I²=0%; 3 studies; low CoE). No study reported quality of life as an outcome. |
| first_indexed | 2024-12-13T19:32:06Z |
| format | Article |
| id | doaj.art-5c815150f2ab4f38be41b5efcf7e96a1 |
| institution | Directory Open Access Journal |
| issn | 2287-4208 2287-4690 |
| language | English |
| last_indexed | 2024-12-13T19:32:06Z |
| publishDate | 2022-04-01 |
| publisher | Korean Society for Sexual Medicine and Andrology |
| record_format | Article |
| series | The World Journal of Men's Health |
| spelling | doaj.art-5c815150f2ab4f38be41b5efcf7e96a12022-12-21T23:33:54ZengKorean Society for Sexual Medicine and AndrologyThe World Journal of Men's Health2287-42082287-46902022-04-0140226426910.5534/wjmh.210071Ginseng for Erectile Dysfunction: A Cochrane Systematic ReviewHye Won Lee0https://orcid.org/0000-0003-4248-1482Myeong Soo Lee1https://orcid.org/0000-0001-6651-7641Tae-Hun Kim2https://orcid.org/0000-0002-8448-3219Terje Alraek3https://orcid.org/0000-0001-6876-1699Chris Zaslawski4https://orcid.org/0000-0001-5618-5161Jong Wook Kim5https://orcid.org/0000-0003-2228-0640Du Geon Moon6https://orcid.org/0000-0002-9031-9845Korea Institute of Oriental MedicineKorea Institute of Oriental MedicineKyung Hee University, Seoul, KoreaKristiania University College, OsloUniversity of Technology, Sydney, AustraliaDepartment of Urology, Korea University Guro Hospital, Seoul, KoreaDepartment of Urology, Korea University Guro Hospital, Seoul, KoreaThe objectives of this study were to assess the effects of ginseng on erectile dysfunction. We searched multiple electronic databases from their inceptions to 30 January 2021 without restrictions by language. We included randomized or quasirandomized controlled trials that evaluated the use of any type of ginseng as a treatment for erectile dysfunction compared to placebo or conventional treatment. The authors independently screened the literature, extracted data, assessed risk of bias, and rated the certainty of evidence (CoE) according to the GRADE approach. We included nine studies, and all compared ginseng to placebo. Ginseng appears to have a trivial effect on erectile dysfunction when compared to placebo based on the Erectile Function Domain of the International Index of Erectile Function (IIEF)-15 instrument (mean difference [MD] 3.52, 95% confidence interval [CI] 1.79 to 5.25; I²=0%; 3 studies; low CoE). Ginseng may have little to no effect on adverse events compared to placebo (risk ratio [RR] 1.45, 95% CI 0.69 to 3.03; I²=0%; 7 studies; low CoE). While ginseng may improve men's self-reported ability to have intercourse (RR 2.55, 95% CI 1.76 to 3.69; I²=23%; 6 studies; low CoE), it may have a trivial effect on men's satisfaction with intercourse based on the Intercourse Satisfaction Domain of the IIEF-15 (MD 1.19, 95% CI 0.41 to 1.97; I²=0%; 3 studies; low CoE). No study reported quality of life as an outcome.erectile dysfunctionginsengmeta-analysispanaxsystematic review |
| spellingShingle | Hye Won Lee Myeong Soo Lee Tae-Hun Kim Terje Alraek Chris Zaslawski Jong Wook Kim Du Geon Moon Ginseng for Erectile Dysfunction: A Cochrane Systematic Review The World Journal of Men's Health erectile dysfunction ginseng meta-analysis panax systematic review |
| title | Ginseng for Erectile Dysfunction: A Cochrane Systematic Review |
| title_full | Ginseng for Erectile Dysfunction: A Cochrane Systematic Review |
| title_fullStr | Ginseng for Erectile Dysfunction: A Cochrane Systematic Review |
| title_full_unstemmed | Ginseng for Erectile Dysfunction: A Cochrane Systematic Review |
| title_short | Ginseng for Erectile Dysfunction: A Cochrane Systematic Review |
| title_sort | ginseng for erectile dysfunction a cochrane systematic review |
| topic | erectile dysfunction ginseng meta-analysis panax systematic review |
| work_keys_str_mv | AT hyewonlee ginsengforerectiledysfunctionacochranesystematicreview AT myeongsoolee ginsengforerectiledysfunctionacochranesystematicreview AT taehunkim ginsengforerectiledysfunctionacochranesystematicreview AT terjealraek ginsengforerectiledysfunctionacochranesystematicreview AT chriszaslawski ginsengforerectiledysfunctionacochranesystematicreview AT jongwookkim ginsengforerectiledysfunctionacochranesystematicreview AT dugeonmoon ginsengforerectiledysfunctionacochranesystematicreview |