Knockdown of FKBP3 suppresses nasopharyngeal carcinoma cell growth, invasion and migration, deactivated NF-κB/IL-6 signaling pathway through inhibiting histone deacetylase 2 expression

Knockdown of FKBP3 suppresses nasopharyngeal carcinoma cell growth, invasion and migration, deactivated NF-κB/IL-6 signaling pathway through inhibiting histone deacetylase 2 expression

Nasopharyngeal carcinoma (NPC) is a prevalent malignant tumor worldwide. FKBP3 has been reported to participate in tumorigenesis. Nevertheless, the role and mechanism of FKBP3 in NPC remains unclear. In this study, FKBP3 expression was observed to upregulate in NPC patients and cells. Moreover, knoc...

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Bibliographic Details
Main Authors: Jiadi Dong, Jingjing Chen, Qun Li, Shijie Qiu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Chinese Journal of Physiology
Subjects:
histone deacetylase 2
interleukin-6
invasion
migration
nasopharyngeal carcinoma
nuclear factor-κb
Online Access:http://www.cjphysiology.org/article.asp?issn=0304-4920;year=2023;volume=66;issue=2;spage=85;epage=92;aulast=Dong

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