Neurotrophic Factors in Parkinson’s Disease: Clinical Trials, Open Challenges and Nanoparticle-Mediated Delivery to the Brain

Neurotrophic Factors in Parkinson’s Disease: Clinical Trials, Open Challenges and Nanoparticle-Mediated Delivery to the Brain

Neurotrophic factors (NTFs) are small secreted proteins that support the development, maturation and survival of neurons. NTFs injected into the brain rescue and regenerate certain neuronal populations lost in neurodegenerative diseases, demonstrating the potential of NTFs to cure the diseases rathe...

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Bibliographic Details
Main Authors:	Olesja Bondarenko, Mart Saarma
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-06-01
Series:	Frontiers in Cellular Neuroscience
Subjects:	Parkinson’s disease brain-derived neurotrophic factor cerebral dopamine neurotrophic factor dopamine neurons endoplasmic reticulum stress glial cell line-derived neurotrophic factor
Online Access:	https://www.frontiersin.org/articles/10.3389/fncel.2021.682597/full

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