Effect of Hexavalent Chromium on Electron Leakage of Respiratory Chain in Mitochondria Isolated from Rat Liver

Effect of Hexavalent Chromium on Electron Leakage of Respiratory Chain in Mitochondria Isolated from Rat Liver

Background/Aims: In the present study, we explored reactive axygen species (ROS) production in mitochondria, the mechanism of hexavalent chromium (Cr(VI)) hepatotoxicity, and the role of protection by GSH. Methods: Intact mitochondria were isolated from rat liver tissues and mitochondrial basal resp...

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Bibliographic Details
Main Authors: Ying Xie, Caigao Zhong, Ming Zeng, Lan Guan, Lei Luo
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-03-01
Series:Cellular Physiology and Biochemistry
Subjects:
Mitochondria
Hepatocyte
Electron leak
GSH
Online Access:http://www.karger.com/Article/FullText/350062

Internet

http://www.karger.com/Article/FullText/350062

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