PAIN SYNDROME IN OSTEOARTHROSIS
By using osteoarthrosis as an example, the author proposes a model to analyze the pain syndrome that may comprise intraorgan, paraorgan and comorbidity-associated pains. The implication of synovitis in the pathogenesis is analyzed. By enhancing the degradation and degeneration of the articular carti...
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| Format: | Article |
| Language: | Russian |
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IMA-PRESS LLC
2009-06-01
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| Series: | Неврология, нейропсихиатрия, психосоматика |
| Subjects: | |
| Online Access: | https://nnp.ima-press.net/nnp/article/view/27 |
| _version_ | 1797876567366434816 |
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| author | N. A. Khitrov |
| author_facet | N. A. Khitrov |
| author_sort | N. A. Khitrov |
| collection | DOAJ |
| description | By using osteoarthrosis as an example, the author proposes a model to analyze the pain syndrome that may comprise intraorgan, paraorgan and comorbidity-associated pains. The implication of synovitis in the pathogenesis is analyzed. By enhancing the degradation and degeneration of the articular cartilage and subchondral bone, synovitis alters cardinally the pain syndrome towards it chronization in osteoarthrosis, drastically lowering a patientXs quality of life. The anti-inflammatory analgesic Amelotex from a group of selective cyclooxygenase 2 inhibitors should be used to combat the pain that underlies the clinical manifestations of osteoarthrosis and largely determines other symptoms. The use of Amelotex in 20 patients with gonarthrosis in a phase of synovitis has demonstrated its rapid anti-inflammatory and analgesic effects. Its adverse reactions are minimal |
| first_indexed | 2024-04-10T02:05:19Z |
| format | Article |
| id | doaj.art-5c8bd14909494f2fa96abd0745768efe |
| institution | Directory Open Access Journal |
| issn | 2074-2711 2310-1342 |
| language | Russian |
| last_indexed | 2024-04-10T02:05:19Z |
| publishDate | 2009-06-01 |
| publisher | IMA-PRESS LLC |
| record_format | Article |
| series | Неврология, нейропсихиатрия, психосоматика |
| spelling | doaj.art-5c8bd14909494f2fa96abd0745768efe2023-03-13T08:42:10ZrusIMA-PRESS LLCНеврология, нейропсихиатрия, психосоматика2074-27112310-13422009-06-0112626710.14412/2074-2711-2009-4127PAIN SYNDROME IN OSTEOARTHROSISN. A. Khitrov0Training-Research Medical Center Department for Presidential Affairs of the Russian FederationBy using osteoarthrosis as an example, the author proposes a model to analyze the pain syndrome that may comprise intraorgan, paraorgan and comorbidity-associated pains. The implication of synovitis in the pathogenesis is analyzed. By enhancing the degradation and degeneration of the articular cartilage and subchondral bone, synovitis alters cardinally the pain syndrome towards it chronization in osteoarthrosis, drastically lowering a patientXs quality of life. The anti-inflammatory analgesic Amelotex from a group of selective cyclooxygenase 2 inhibitors should be used to combat the pain that underlies the clinical manifestations of osteoarthrosis and largely determines other symptoms. The use of Amelotex in 20 patients with gonarthrosis in a phase of synovitis has demonstrated its rapid anti-inflammatory and analgesic effects. Its adverse reactions are minimalhttps://nnp.ima-press.net/nnp/article/view/27osteoarthrosisknee arthrosispain syndromesynovitisnonsteroidal anti-inflammatory drugsamelotex |
| spellingShingle | N. A. Khitrov PAIN SYNDROME IN OSTEOARTHROSIS Неврология, нейропсихиатрия, психосоматика osteoarthrosis knee arthrosis pain syndrome synovitis nonsteroidal anti-inflammatory drugs amelotex |
| title | PAIN SYNDROME IN OSTEOARTHROSIS |
| title_full | PAIN SYNDROME IN OSTEOARTHROSIS |
| title_fullStr | PAIN SYNDROME IN OSTEOARTHROSIS |
| title_full_unstemmed | PAIN SYNDROME IN OSTEOARTHROSIS |
| title_short | PAIN SYNDROME IN OSTEOARTHROSIS |
| title_sort | pain syndrome in osteoarthrosis |
| topic | osteoarthrosis knee arthrosis pain syndrome synovitis nonsteroidal anti-inflammatory drugs amelotex |
| url | https://nnp.ima-press.net/nnp/article/view/27 |
| work_keys_str_mv | AT nakhitrov painsyndromeinosteoarthrosis |