Risk of underdiagnosis of hypertension in schizophrenia patients

Aim: Arterial hypertension requires proper screening and management, and its underdiagnosis in patients with schizophrenia (SZ) and/or antipsychotic treatment has been postulated. The objective of the study is to assess whether there are differences in the proportion of screened patients with a bloo...

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Main Authors: Miguel Castillo-Sánchez, Mireia Fàbregas-Escurriola, Daniel Bergè-Baquero, MªIsabel Fernández-San Martín, Quintí Foguet Boreu, Albert Goday-Arno
Format: Article
Language:English
Published: Taylor & Francis Group 2018-02-01
Series:Clinical and Experimental Hypertension
Subjects:
Online Access:http://dx.doi.org/10.1080/10641963.2017.1346114
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author Miguel Castillo-Sánchez
Mireia Fàbregas-Escurriola
Daniel Bergè-Baquero
MªIsabel Fernández-San Martín
Quintí Foguet Boreu
Albert Goday-Arno
author_facet Miguel Castillo-Sánchez
Mireia Fàbregas-Escurriola
Daniel Bergè-Baquero
MªIsabel Fernández-San Martín
Quintí Foguet Boreu
Albert Goday-Arno
author_sort Miguel Castillo-Sánchez
collection DOAJ
description Aim: Arterial hypertension requires proper screening and management, and its underdiagnosis in patients with schizophrenia (SZ) and/or antipsychotic treatment has been postulated. The objective of the study is to assess whether there are differences in the proportion of screened patients with a blood pressure >140/90 mmHg that are undiagnosed or not confirmed later (risk of underdiagnosis). Methods: Cross-sectional study of clinical records from SIDIAPQ (Spain) during the 2006–2011 period. Three groups were studied: SZ, no SZ but under antipsychotic treatment, and control groups. Patients with established hypertension, cardiovascular disease, dementia, or diagnosis of SZ or starting with antipsychotic treatment during this period were excluded. Results: The SZ group had a lower risk of underdiagnosis than the control group (OR 0.91; 95% CI: 0.83–0.99; p < 0.05), at the expense of men (OR 0.8; 95% CI: 0.71–0.9; p < 0.001) and patients younger than 50 years of age (OR: 0.84; 95% CI: 0.74–0.93; p < 0.003). In the no SZ but under antipsychotic treatment group there were some differences, but not in the overall results. Conclusion: Preventive management of hypertension seemed to be sufficient for SZ and antipsychotic treatment patients. The lower prevalence of hypertension found in these groups may be due to other factors (blood pressure-lowering effect of psychoactive drugs or smoking) but these hypotheses must be evaluated with specific studies.
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spelling doaj.art-5c8c74a200f14616b632185f177e23f32023-09-19T15:19:26ZengTaylor & Francis GroupClinical and Experimental Hypertension1064-19631525-60062018-02-0140216717410.1080/10641963.2017.13461141346114Risk of underdiagnosis of hypertension in schizophrenia patientsMiguel Castillo-Sánchez0Mireia Fàbregas-Escurriola1Daniel Bergè-Baquero2MªIsabel Fernández-San Martín3Quintí Foguet Boreu4Albert Goday-Arno5Universitat Autònoma de BarcelonaGrupo de Trastornos Mentales Severos, Institut Universitari d’Investigaciò en Atenciò Primaria (IDIAP) Jordi GolInstitut de Neuropsiquiatria i Addiccions, Parc de Salut MarGrupo de Trastornos Mentales Severos, Institut Universitari d’Investigaciò en Atenciò Primaria (IDIAP) Jordi GolGrupo de Trastornos Mentales Severos, Institut Universitari d’Investigaciò en Atenciò Primaria (IDIAP) Jordi GolUniversitat Autònoma de BarcelonaAim: Arterial hypertension requires proper screening and management, and its underdiagnosis in patients with schizophrenia (SZ) and/or antipsychotic treatment has been postulated. The objective of the study is to assess whether there are differences in the proportion of screened patients with a blood pressure >140/90 mmHg that are undiagnosed or not confirmed later (risk of underdiagnosis). Methods: Cross-sectional study of clinical records from SIDIAPQ (Spain) during the 2006–2011 period. Three groups were studied: SZ, no SZ but under antipsychotic treatment, and control groups. Patients with established hypertension, cardiovascular disease, dementia, or diagnosis of SZ or starting with antipsychotic treatment during this period were excluded. Results: The SZ group had a lower risk of underdiagnosis than the control group (OR 0.91; 95% CI: 0.83–0.99; p < 0.05), at the expense of men (OR 0.8; 95% CI: 0.71–0.9; p < 0.001) and patients younger than 50 years of age (OR: 0.84; 95% CI: 0.74–0.93; p < 0.003). In the no SZ but under antipsychotic treatment group there were some differences, but not in the overall results. Conclusion: Preventive management of hypertension seemed to be sufficient for SZ and antipsychotic treatment patients. The lower prevalence of hypertension found in these groups may be due to other factors (blood pressure-lowering effect of psychoactive drugs or smoking) but these hypotheses must be evaluated with specific studies.http://dx.doi.org/10.1080/10641963.2017.1346114antipsychotic agentscardiovascular diseaseshypertensionprimary health careschizophrenia
spellingShingle Miguel Castillo-Sánchez
Mireia Fàbregas-Escurriola
Daniel Bergè-Baquero
MªIsabel Fernández-San Martín
Quintí Foguet Boreu
Albert Goday-Arno
Risk of underdiagnosis of hypertension in schizophrenia patients
Clinical and Experimental Hypertension
antipsychotic agents
cardiovascular diseases
hypertension
primary health care
schizophrenia
title Risk of underdiagnosis of hypertension in schizophrenia patients
title_full Risk of underdiagnosis of hypertension in schizophrenia patients
title_fullStr Risk of underdiagnosis of hypertension in schizophrenia patients
title_full_unstemmed Risk of underdiagnosis of hypertension in schizophrenia patients
title_short Risk of underdiagnosis of hypertension in schizophrenia patients
title_sort risk of underdiagnosis of hypertension in schizophrenia patients
topic antipsychotic agents
cardiovascular diseases
hypertension
primary health care
schizophrenia
url http://dx.doi.org/10.1080/10641963.2017.1346114
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AT maisabelfernandezsanmartin riskofunderdiagnosisofhypertensioninschizophreniapatients
AT quintifoguetboreu riskofunderdiagnosisofhypertensioninschizophreniapatients
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