Polysomnographic Aspects of Sleep Architecture on Self-limited Epilepsy with Centrotemporal Spikes: A Systematic Review and Meta-analysis
Self-limited epilepsy with centrotemporal spikes is the most common paediatric epileptic syndrome, with growing evidence linking it to various degrees and presentations of neuropsychological dysfunction. The objective of this study is to evaluate the possible sleep macro a...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Thieme Revinter Publicações Ltda.
|
| Series: | Sleep Science |
| Subjects: | |
| Online Access: | http://sleepscience.org.br/export-pdf/415/v10n4a05.pdf |
| _version_ | 1827392326905888768 |
|---|---|
| author | Camila dos Santos Halal Bernardo Lessa Horta Magda Lahorgue Nunes |
| author_facet | Camila dos Santos Halal Bernardo Lessa Horta Magda Lahorgue Nunes |
| author_sort | Camila dos Santos Halal |
| collection | DOAJ |
| description | Self-limited epilepsy with centrotemporal spikes is the most common
paediatric epileptic syndrome, with growing evidence linking it to various degrees and
presentations of neuropsychological dysfunction. The objective of this study is to evaluate
the possible sleep macro and microstructural alterations in children with this diagnosis. A
systematic review of published manuscripts was carried out in Medline, LILACS and Scielo
databases, using the MeSH terms epilepsy, sleep and
polysomnography. From 753 retrieved references, 5 were selected, and
data from macro and, when available, microstructure of sleep were extracted. Meta-analysis
was performed with data from 4 studies using standardized mean difference. Findings were
heterogeneous between studies, being the most frequent macrostructural findings a smaller
proportion and greater latency of REM sleep in two studies and, in meta-analysis, a longer
sleep latency was the most significant finding among epileptic patients. Only one study
evaluated sleep microstructure, suggesting possible alterations in cyclic alternating
pattern in diagnosed children. Studies evaluating macro and microstructure of sleep in
children with self-limited epilepsy with centrotemporal spikes are necessary to a better
understanding of mechanisms of the neuropsychologic disturbances that are frequently seen
in children with this diagnosis. |
| first_indexed | 2024-03-08T17:29:39Z |
| format | Article |
| id | doaj.art-5c9375c2c58a4db7ab88a64744ba2261 |
| institution | Directory Open Access Journal |
| issn | 1984-0659 1984-0063 |
| language | English |
| last_indexed | 2024-03-08T17:29:39Z |
| publisher | Thieme Revinter Publicações Ltda. |
| record_format | Article |
| series | Sleep Science |
| spelling | doaj.art-5c9375c2c58a4db7ab88a64744ba22612024-01-02T16:07:31ZengThieme Revinter Publicações Ltda.Sleep Science1984-06591984-006310416116710.5935/1984-0063.20170028Polysomnographic Aspects of Sleep Architecture on Self-limited Epilepsy with Centrotemporal Spikes: A Systematic Review and Meta-analysisCamila dos Santos Halal0Bernardo Lessa Horta1Magda Lahorgue Nunes2 Pontificia Universidade Católica do Rio Grande do Sul (PUCRS), PhD Program of Medicine and Health Sciences - Porto Alegre - Rio Grande do Sul - Brazil Universidade Federal de Pelotas, Postgraduate Program in Epidemiology, Pelotas, Rio Grande do Sul, Brazil Pontifícia Universidade Católica do Rio Grande do Sul School of Medicine and Brain Institute (BRAIns), Division of Neurology, Porto Alebre, Rio Grande do Sul, BrazilSelf-limited epilepsy with centrotemporal spikes is the most common paediatric epileptic syndrome, with growing evidence linking it to various degrees and presentations of neuropsychological dysfunction. The objective of this study is to evaluate the possible sleep macro and microstructural alterations in children with this diagnosis. A systematic review of published manuscripts was carried out in Medline, LILACS and Scielo databases, using the MeSH terms epilepsy, sleep and polysomnography. From 753 retrieved references, 5 were selected, and data from macro and, when available, microstructure of sleep were extracted. Meta-analysis was performed with data from 4 studies using standardized mean difference. Findings were heterogeneous between studies, being the most frequent macrostructural findings a smaller proportion and greater latency of REM sleep in two studies and, in meta-analysis, a longer sleep latency was the most significant finding among epileptic patients. Only one study evaluated sleep microstructure, suggesting possible alterations in cyclic alternating pattern in diagnosed children. Studies evaluating macro and microstructure of sleep in children with self-limited epilepsy with centrotemporal spikes are necessary to a better understanding of mechanisms of the neuropsychologic disturbances that are frequently seen in children with this diagnosis.http://sleepscience.org.br/export-pdf/415/v10n4a05.pdfSleepEpilepsyPolysomnography |
| spellingShingle | Camila dos Santos Halal Bernardo Lessa Horta Magda Lahorgue Nunes Polysomnographic Aspects of Sleep Architecture on Self-limited Epilepsy with Centrotemporal Spikes: A Systematic Review and Meta-analysis Sleep Science Sleep Epilepsy Polysomnography |
| title | Polysomnographic Aspects of Sleep Architecture on Self-limited Epilepsy
with Centrotemporal Spikes: A Systematic Review and Meta-analysis |
| title_full | Polysomnographic Aspects of Sleep Architecture on Self-limited Epilepsy
with Centrotemporal Spikes: A Systematic Review and Meta-analysis |
| title_fullStr | Polysomnographic Aspects of Sleep Architecture on Self-limited Epilepsy
with Centrotemporal Spikes: A Systematic Review and Meta-analysis |
| title_full_unstemmed | Polysomnographic Aspects of Sleep Architecture on Self-limited Epilepsy
with Centrotemporal Spikes: A Systematic Review and Meta-analysis |
| title_short | Polysomnographic Aspects of Sleep Architecture on Self-limited Epilepsy
with Centrotemporal Spikes: A Systematic Review and Meta-analysis |
| title_sort | polysomnographic aspects of sleep architecture on self limited epilepsy with centrotemporal spikes a systematic review and meta analysis |
| topic | Sleep Epilepsy Polysomnography |
| url | http://sleepscience.org.br/export-pdf/415/v10n4a05.pdf |
| work_keys_str_mv | AT camiladossantoshalal polysomnographicaspectsofsleeparchitectureonselflimitedepilepsywithcentrotemporalspikesasystematicreviewandmetaanalysis AT bernardolessahorta polysomnographicaspectsofsleeparchitectureonselflimitedepilepsywithcentrotemporalspikesasystematicreviewandmetaanalysis AT magdalahorguenunes polysomnographicaspectsofsleeparchitectureonselflimitedepilepsywithcentrotemporalspikesasystematicreviewandmetaanalysis |