Current Role of Delta Radiomics in Head and Neck Oncology

The latest developments in the management of head and neck cancer show an increasing trend in the implementation of novel approaches using artificial intelligence for better patient stratification and treatment-related risk evaluation. Radiomics, or the extraction of data from various imaging modali...

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Main Authors: David C. Marcu, Cristian Grava, Loredana G. Marcu
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/3/2214
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author David C. Marcu
Cristian Grava
Loredana G. Marcu
author_facet David C. Marcu
Cristian Grava
Loredana G. Marcu
author_sort David C. Marcu
collection DOAJ
description The latest developments in the management of head and neck cancer show an increasing trend in the implementation of novel approaches using artificial intelligence for better patient stratification and treatment-related risk evaluation. Radiomics, or the extraction of data from various imaging modalities, is a tool often used to evaluate specific features related to the tumour or normal tissue that are not identifiable by the naked eye and which can add value to existing clinical data. Furthermore, the assessment of feature variations from one time point to another based on subsequent images, known as delta radiomics, was shown to have even higher value for treatment-outcome prediction or patient stratification into risk categories. The information gathered from delta radiomics can, further, be used for decision making regarding treatment adaptation or other interventions found to be beneficial to the patient. The aim of this work is to collate the existing studies on delta radiomics in head and neck cancer and evaluate its role in tumour response and normal-tissue toxicity predictions alike. Moreover, this work also highlights the role of holomics, which brings under the same umbrella clinical and radiomic features, for a more complex patient characterization and treatment optimisation.
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spelling doaj.art-5c97d00db1414918b751d6b38552545f2023-11-16T16:53:59ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672023-01-01243221410.3390/ijms24032214Current Role of Delta Radiomics in Head and Neck OncologyDavid C. Marcu0Cristian Grava1Loredana G. Marcu2Faculty of Electrical Engineering & Information Technology, University of Oradea, 410087 Oradea, RomaniaFaculty of Electrical Engineering & Information Technology, University of Oradea, 410087 Oradea, RomaniaFaculty of Informatics & Science, University of Oradea, 410087 Oradea, RomaniaThe latest developments in the management of head and neck cancer show an increasing trend in the implementation of novel approaches using artificial intelligence for better patient stratification and treatment-related risk evaluation. Radiomics, or the extraction of data from various imaging modalities, is a tool often used to evaluate specific features related to the tumour or normal tissue that are not identifiable by the naked eye and which can add value to existing clinical data. Furthermore, the assessment of feature variations from one time point to another based on subsequent images, known as delta radiomics, was shown to have even higher value for treatment-outcome prediction or patient stratification into risk categories. The information gathered from delta radiomics can, further, be used for decision making regarding treatment adaptation or other interventions found to be beneficial to the patient. The aim of this work is to collate the existing studies on delta radiomics in head and neck cancer and evaluate its role in tumour response and normal-tissue toxicity predictions alike. Moreover, this work also highlights the role of holomics, which brings under the same umbrella clinical and radiomic features, for a more complex patient characterization and treatment optimisation.https://www.mdpi.com/1422-0067/24/3/2214radiomicssequential imagingradiotherapychemotherapyadaptive treatmentoutcome prediction
spellingShingle David C. Marcu
Cristian Grava
Loredana G. Marcu
Current Role of Delta Radiomics in Head and Neck Oncology
International Journal of Molecular Sciences
radiomics
sequential imaging
radiotherapy
chemotherapy
adaptive treatment
outcome prediction
title Current Role of Delta Radiomics in Head and Neck Oncology
title_full Current Role of Delta Radiomics in Head and Neck Oncology
title_fullStr Current Role of Delta Radiomics in Head and Neck Oncology
title_full_unstemmed Current Role of Delta Radiomics in Head and Neck Oncology
title_short Current Role of Delta Radiomics in Head and Neck Oncology
title_sort current role of delta radiomics in head and neck oncology
topic radiomics
sequential imaging
radiotherapy
chemotherapy
adaptive treatment
outcome prediction
url https://www.mdpi.com/1422-0067/24/3/2214
work_keys_str_mv AT davidcmarcu currentroleofdeltaradiomicsinheadandneckoncology
AT cristiangrava currentroleofdeltaradiomicsinheadandneckoncology
AT loredanagmarcu currentroleofdeltaradiomicsinheadandneckoncology