DoGNet: A deep architecture for synapse detection in multiplexed fluorescence images.
Neuronal synapses transmit electrochemical signals between cells through the coordinated action of presynaptic vesicles, ion channels, scaffolding and adapter proteins, and membrane receptors. In situ structural characterization of numerous synaptic proteins simultaneously through multiplexed imagin...
Main Authors: | Victor Kulikov, Syuan-Ming Guo, Matthew Stone, Allen Goodman, Anne Carpenter, Mark Bathe, Victor Lempitsky |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-05-01
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Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.1007012 |
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