Dynamic, large-scale profiling of transcription factor activity from live cells in 3D culture.

Dynamic, large-scale profiling of transcription factor activity from live cells in 3D culture.

Extracellular activation of signal transduction pathways and their downstream target transcription factors (TFs) are critical regulators of cellular processes and tissue development. The intracellular signaling network is complex, and techniques that quantify the activities of numerous pathways and...

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Bibliographic Details
Main Authors: Michael S Weiss, Beatriz Peñalver Bernabé, Abigail D Bellis, Linda J Broadbelt, Jacqueline S Jeruss, Lonnie D Shea
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2984444?pdf=render

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