Daphnetin Alleviates Bleomycin-Induced Pulmonary Fibrosis through Inhibition of Epithelial-to-Mesenchymal Transition and IL-17A

Daphnetin Alleviates Bleomycin-Induced Pulmonary Fibrosis through Inhibition of Epithelial-to-Mesenchymal Transition and IL-17A

Idiopathic pulmonary fibrosis (IPF) is a chronic and refractory interstitial lung disease. Although there is no cure for IPF, the development of drugs with improved efficacy in the treatment of IPF is required. Daphnetin, a natural coumarin derivative, has immunosuppressive, anti-inflammatory, and a...

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Bibliographic Details
Main Authors: Soo-Jin Park, Hyung Won Ryu, Ji-Hyeong Kim, Hwa-Jeong Hahn, Hyun-Jae Jang, Sung-Kyun Ko, Sei-Ryang Oh, Hyun-Jun Lee
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Cells
Subjects:
daphnetin
idiopathic pulmonary fibrosis
TGF-β
Th17
IL-17A
Online Access:https://www.mdpi.com/2073-4409/12/24/2795

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