Effect of Surfactants and Polymers on the Dissolution Behavior of Supersaturable Tecovirimat-4-Hydroxybenzoic Acid Cocrystals

Effect of Surfactants and Polymers on the Dissolution Behavior of Supersaturable Tecovirimat-4-Hydroxybenzoic Acid Cocrystals

(1) Background: Pharmaceutical cocrystals have attracted remarkable interest and have been successfully used to enhance the absorption of poorly water-soluble drugs. However, supersaturable cocrystals are sometimes thermodynamically unstable, and the solubility advantages present a risk of precipita...

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Bibliographic Details
Main Authors: Yumiao Feng, Yuanyuan Meng, Fangyun Tan, Lin Lv, Zhiping Li, Yuli Wang, Yang Yang, Wei Gong, Meiyan Yang
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Pharmaceutics
Subjects:
cocrystals
dissolution
solubility
supersaturation
surfactant
polymer
Online Access:https://www.mdpi.com/1999-4923/13/11/1772

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