Analysis of Organic Sulphur Compounds in Coal Tar by Using Comprehensive Two-Dimensional Gas Chromatography-High Resolution Time-of-Flight Mass Spectrometry
Coal tar is a complex mixture of organic compounds obtained from the thermal treatment of coal; it contains several different chemical classes of compounds, such as polycyclic aromatic hydrocarbons, phenols and different heterocyclic compounds including sulphur derivatives. In the present research,...
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MDPI AG
2020-05-01
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| Online Access: | https://www.mdpi.com/2297-8739/7/2/26 |
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| author | Ivan Aloisi Mariosimone Zoccali Peter Q. Tranchida Luigi Mondello |
| author_facet | Ivan Aloisi Mariosimone Zoccali Peter Q. Tranchida Luigi Mondello |
| author_sort | Ivan Aloisi |
| collection | DOAJ |
| description | Coal tar is a complex mixture of organic compounds obtained from the thermal treatment of coal; it contains several different chemical classes of compounds, such as polycyclic aromatic hydrocarbons, phenols and different heterocyclic compounds including sulphur derivatives. In the present research, a target analysis was carried out for the characterisation of fourteen different classes of organic sulphur compounds in coal tar by using cryogenically-modulated (CM) comprehensive two-dimensional gas chromatography-high resolution time-of-flight mass spectrometry (GC×GC-HR ToFMS) with the support of target analyte finding, a specific software function. Furthermore, absolute quantification data were obtained by using eight pure standard sulphur compounds, and 1-fluoronaphthalene as internal standard. Several figures-of-merit of the proposed method were measured (linearity, intra-day precision, limits of detection and quantification). Finally, the overall analytical performance of CM GC×GC-HR ToFMS was evaluated, in relation to MS similarities, mass accuracies, second-dimension peak widths, peak capacity and tailing factors. The approach proved itself as being a powerful analytical platform, benefiting from the high sensitivity, selectivity and resolving power, of both the GC and MS sides. |
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| institution | Directory Open Access Journal |
| issn | 2297-8739 |
| language | English |
| last_indexed | 2024-03-10T19:56:21Z |
| publishDate | 2020-05-01 |
| publisher | MDPI AG |
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| spelling | doaj.art-5ca24cdfc9d64ad489cc2a4a5f0678a92023-11-19T23:53:18ZengMDPI AGSeparations2297-87392020-05-01722610.3390/separations7020026Analysis of Organic Sulphur Compounds in Coal Tar by Using Comprehensive Two-Dimensional Gas Chromatography-High Resolution Time-of-Flight Mass SpectrometryIvan Aloisi0Mariosimone Zoccali1Peter Q. Tranchida2Luigi Mondello3Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, 98168 Messina, ItalyDepartment of Mathematical and Computational Sciences, Physical Science and Earth Science, University of Messina, 98166 Messina, ItalyDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, 98168 Messina, ItalyDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, 98168 Messina, ItalyCoal tar is a complex mixture of organic compounds obtained from the thermal treatment of coal; it contains several different chemical classes of compounds, such as polycyclic aromatic hydrocarbons, phenols and different heterocyclic compounds including sulphur derivatives. In the present research, a target analysis was carried out for the characterisation of fourteen different classes of organic sulphur compounds in coal tar by using cryogenically-modulated (CM) comprehensive two-dimensional gas chromatography-high resolution time-of-flight mass spectrometry (GC×GC-HR ToFMS) with the support of target analyte finding, a specific software function. Furthermore, absolute quantification data were obtained by using eight pure standard sulphur compounds, and 1-fluoronaphthalene as internal standard. Several figures-of-merit of the proposed method were measured (linearity, intra-day precision, limits of detection and quantification). Finally, the overall analytical performance of CM GC×GC-HR ToFMS was evaluated, in relation to MS similarities, mass accuracies, second-dimension peak widths, peak capacity and tailing factors. The approach proved itself as being a powerful analytical platform, benefiting from the high sensitivity, selectivity and resolving power, of both the GC and MS sides.https://www.mdpi.com/2297-8739/7/2/26comprehensive two-dimensional gas chromatographyhigh resolution time-of-flight mass spectrometrycoal tarorganic sulphur compounds |
| spellingShingle | Ivan Aloisi Mariosimone Zoccali Peter Q. Tranchida Luigi Mondello Analysis of Organic Sulphur Compounds in Coal Tar by Using Comprehensive Two-Dimensional Gas Chromatography-High Resolution Time-of-Flight Mass Spectrometry Separations comprehensive two-dimensional gas chromatography high resolution time-of-flight mass spectrometry coal tar organic sulphur compounds |
| title | Analysis of Organic Sulphur Compounds in Coal Tar by Using Comprehensive Two-Dimensional Gas Chromatography-High Resolution Time-of-Flight Mass Spectrometry |
| title_full | Analysis of Organic Sulphur Compounds in Coal Tar by Using Comprehensive Two-Dimensional Gas Chromatography-High Resolution Time-of-Flight Mass Spectrometry |
| title_fullStr | Analysis of Organic Sulphur Compounds in Coal Tar by Using Comprehensive Two-Dimensional Gas Chromatography-High Resolution Time-of-Flight Mass Spectrometry |
| title_full_unstemmed | Analysis of Organic Sulphur Compounds in Coal Tar by Using Comprehensive Two-Dimensional Gas Chromatography-High Resolution Time-of-Flight Mass Spectrometry |
| title_short | Analysis of Organic Sulphur Compounds in Coal Tar by Using Comprehensive Two-Dimensional Gas Chromatography-High Resolution Time-of-Flight Mass Spectrometry |
| title_sort | analysis of organic sulphur compounds in coal tar by using comprehensive two dimensional gas chromatography high resolution time of flight mass spectrometry |
| topic | comprehensive two-dimensional gas chromatography high resolution time-of-flight mass spectrometry coal tar organic sulphur compounds |
| url | https://www.mdpi.com/2297-8739/7/2/26 |
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