Immunotherapy and cell therapy as a practical approach in cancer therapy

Cancer treatment is one of the most important challenges in medical science. Most methods such as surgery, chemotherapy, and radiation therapy are not completely effective in treating cancer. In this way, immunotherapy and cell therapy have revolutionized cancer treatment. Immunotherapy and cell th...

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Main Authors: Sogand Vahidi, Seyedeh Elham Norollahi, Ali Akbar Samadani
Format: Article
Language:English
Published: Zabansaraye Parsian Novin Mehr Institute 2022-03-01
Series:Journal of Current Oncology and Medical Sciences
Subjects:
Online Access:http://submission.journalofcoms.com/index.php/JCOMS/article/view/31
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author Sogand Vahidi
Seyedeh Elham Norollahi
Ali Akbar Samadani
author_facet Sogand Vahidi
Seyedeh Elham Norollahi
Ali Akbar Samadani
author_sort Sogand Vahidi
collection DOAJ
description Cancer treatment is one of the most important challenges in medical science. Most methods such as surgery, chemotherapy, and radiation therapy are not completely effective in treating cancer. In this way, immunotherapy and cell therapy have revolutionized cancer treatment. Immunotherapy and cell therapy, like chemotherapy, are given systemically and are effective in preventing the spread of malignancies, but in contrast, they only attack malignant cells and have little effect on their cells, and are more specific. Slowly They have completely different efficiencies depending on the different types of immunotherapy, which include selective cell transfer (ACT) and immunosuppressive inhibitors (ICIs). The study of the mechanisms underlying the escape of cancer cells from the immune system is also very important in identifying new cancer treatments. This review discusses the types of immunotherapy and cell therapy in cancer, the history of development, and recent findings on the penetration of immune cells into the tumor and its relationship to cancer immunotherapy, focusing on new studies and its potential clinical applications.
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spelling doaj.art-5cad2f9748524d508422213667f38e542023-03-22T18:32:58ZengZabansaraye Parsian Novin Mehr InstituteJournal of Current Oncology and Medical Sciences2783-31272022-03-0111160167Immunotherapy and cell therapy as a practical approach in cancer therapySogand Vahidi0Seyedeh Elham Norollahi 1Ali Akbar Samadani2 Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, IranCancer Research Center and Department of Immunology, Semnan University of Medical Sciences, Semnan, Iran Department of Basic Medical Sciences, Neyshabur University of Medical Sciences, Neyshabur, Iran / Guilan Road Trauma Research Center, Guilan University of Medical Sciences, Rasht, IranCancer treatment is one of the most important challenges in medical science. Most methods such as surgery, chemotherapy, and radiation therapy are not completely effective in treating cancer. In this way, immunotherapy and cell therapy have revolutionized cancer treatment. Immunotherapy and cell therapy, like chemotherapy, are given systemically and are effective in preventing the spread of malignancies, but in contrast, they only attack malignant cells and have little effect on their cells, and are more specific. Slowly They have completely different efficiencies depending on the different types of immunotherapy, which include selective cell transfer (ACT) and immunosuppressive inhibitors (ICIs). The study of the mechanisms underlying the escape of cancer cells from the immune system is also very important in identifying new cancer treatments. This review discusses the types of immunotherapy and cell therapy in cancer, the history of development, and recent findings on the penetration of immune cells into the tumor and its relationship to cancer immunotherapy, focusing on new studies and its potential clinical applications.http://submission.journalofcoms.com/index.php/JCOMS/article/view/31cancer immunotherapyimmune systemtumortherapy
spellingShingle Sogand Vahidi
Seyedeh Elham Norollahi
Ali Akbar Samadani
Immunotherapy and cell therapy as a practical approach in cancer therapy
Journal of Current Oncology and Medical Sciences
cancer immunotherapy
immune system
tumor
therapy
title Immunotherapy and cell therapy as a practical approach in cancer therapy
title_full Immunotherapy and cell therapy as a practical approach in cancer therapy
title_fullStr Immunotherapy and cell therapy as a practical approach in cancer therapy
title_full_unstemmed Immunotherapy and cell therapy as a practical approach in cancer therapy
title_short Immunotherapy and cell therapy as a practical approach in cancer therapy
title_sort immunotherapy and cell therapy as a practical approach in cancer therapy
topic cancer immunotherapy
immune system
tumor
therapy
url http://submission.journalofcoms.com/index.php/JCOMS/article/view/31
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AT seyedehelhamnorollahi immunotherapyandcelltherapyasapracticalapproachincancertherapy
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