A Review of Omics Studies on Arboviruses: Alphavirus, Orthobunyavirus and Phlebovirus
Since the intricate and complex steps in pathogenesis and host-viral interactions of arthropod-borne viruses or arboviruses are not completely understood, the multi-omics approaches, which encompass proteomics, transcriptomics, genomics and metabolomics network analysis, are of great importance. We...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-10-01
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| Series: | Viruses |
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| Online Access: | https://www.mdpi.com/1999-4915/14/10/2194 |
| _version_ | 1797469626039271424 |
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| author | Rafaela dos S. Peinado Raphael J. Eberle Raghuvir K. Arni Mônika A. Coronado |
| author_facet | Rafaela dos S. Peinado Raphael J. Eberle Raghuvir K. Arni Mônika A. Coronado |
| author_sort | Rafaela dos S. Peinado |
| collection | DOAJ |
| description | Since the intricate and complex steps in pathogenesis and host-viral interactions of arthropod-borne viruses or arboviruses are not completely understood, the multi-omics approaches, which encompass proteomics, transcriptomics, genomics and metabolomics network analysis, are of great importance. We have reviewed the omics studies on mosquito-borne viruses of the <i>Togaviridae</i>, <i>Peribuyaviridae</i> and <i>Phenuiviridae</i> families, specifically for Chikungunya, Mayaro, Oropouche and Rift Valley Fever viruses. Omics studies can potentially provide a new perspective on the pathophysiology of arboviruses, contributing to a better comprehension of these diseases and their effects and, hence, provide novel insights for the development of new antiviral drugs or therapies. |
| first_indexed | 2024-03-09T19:23:31Z |
| format | Article |
| id | doaj.art-5cadb9489ea94e3cb4cf8df416f7ed7e |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-03-09T19:23:31Z |
| publishDate | 2022-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-5cadb9489ea94e3cb4cf8df416f7ed7e2023-11-24T03:09:07ZengMDPI AGViruses1999-49152022-10-011410219410.3390/v14102194A Review of Omics Studies on Arboviruses: Alphavirus, Orthobunyavirus and PhlebovirusRafaela dos S. Peinado0Raphael J. Eberle1Raghuvir K. Arni2Mônika A. Coronado3Multiuser Center for Biomolecular Innovation, Department of Physics, Sao Paulo State University, Sao Jose do Rio Preto 15054-000, SP, BrazilInstitute of Biological Information Processing, IBI-7: Structural Biochemistry, Forschungszentrum Jülich, 52425 Jülich, GermanyMultiuser Center for Biomolecular Innovation, Department of Physics, Sao Paulo State University, Sao Jose do Rio Preto 15054-000, SP, BrazilInstitute of Biological Information Processing, IBI-7: Structural Biochemistry, Forschungszentrum Jülich, 52425 Jülich, GermanySince the intricate and complex steps in pathogenesis and host-viral interactions of arthropod-borne viruses or arboviruses are not completely understood, the multi-omics approaches, which encompass proteomics, transcriptomics, genomics and metabolomics network analysis, are of great importance. We have reviewed the omics studies on mosquito-borne viruses of the <i>Togaviridae</i>, <i>Peribuyaviridae</i> and <i>Phenuiviridae</i> families, specifically for Chikungunya, Mayaro, Oropouche and Rift Valley Fever viruses. Omics studies can potentially provide a new perspective on the pathophysiology of arboviruses, contributing to a better comprehension of these diseases and their effects and, hence, provide novel insights for the development of new antiviral drugs or therapies.https://www.mdpi.com/1999-4915/14/10/2194arbovirusesomicsgenomicstranscriptomicsproteomicsmetabolomics |
| spellingShingle | Rafaela dos S. Peinado Raphael J. Eberle Raghuvir K. Arni Mônika A. Coronado A Review of Omics Studies on Arboviruses: Alphavirus, Orthobunyavirus and Phlebovirus Viruses arboviruses omics genomics transcriptomics proteomics metabolomics |
| title | A Review of Omics Studies on Arboviruses: Alphavirus, Orthobunyavirus and Phlebovirus |
| title_full | A Review of Omics Studies on Arboviruses: Alphavirus, Orthobunyavirus and Phlebovirus |
| title_fullStr | A Review of Omics Studies on Arboviruses: Alphavirus, Orthobunyavirus and Phlebovirus |
| title_full_unstemmed | A Review of Omics Studies on Arboviruses: Alphavirus, Orthobunyavirus and Phlebovirus |
| title_short | A Review of Omics Studies on Arboviruses: Alphavirus, Orthobunyavirus and Phlebovirus |
| title_sort | review of omics studies on arboviruses alphavirus orthobunyavirus and phlebovirus |
| topic | arboviruses omics genomics transcriptomics proteomics metabolomics |
| url | https://www.mdpi.com/1999-4915/14/10/2194 |
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