Effects of Sub-Minimum Inhibitory Concentrations of Imipenem and Colistin on Expression of Biofilm-Specific Antibiotic Resistance and Virulence Genes in <i>Acinetobacter baumannii</i> Sequence Type 1894

Effects of Sub-Minimum Inhibitory Concentrations of Imipenem and Colistin on Expression of Biofilm-Specific Antibiotic Resistance and Virulence Genes in <i>Acinetobacter baumannii</i> Sequence Type 1894

Antibiotics at suboptimal doses promote biofilm formation and the development of antibiotic resistance. The underlying molecular mechanisms, however, were not investigated. Here, we report the effects of sub-minimum inhibitory concentrations (sub-MICs) of imipenem and colistin on genes associated wi...

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Bibliographic Details
Main Authors: Abebe Mekuria Shenkutie, Jiaying Zhang, Mianzhi Yao, Daniel Asrat, Franklin W. N. Chow, Polly H. M. Leung
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Acinetobacter baumannii</i>
biofilm
colistin
imipenem
antibiotic resistance
RNA sequencing
Online Access:https://www.mdpi.com/1422-0067/23/20/12705

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