Challenges in Pharmacological Intervention in Perilipins (PLINs) to Modulate Lipid Droplet Dynamics in Obesity and Cancer

Challenges in Pharmacological Intervention in Perilipins (PLINs) to Modulate Lipid Droplet Dynamics in Obesity and Cancer

Perilipins (PLINs) are the most abundant proteins in lipid droplets (LD). These LD-associated proteins are responsible for upgrading LD from inert lipid storage structures to fully functional organelles, fundamentally integrated in the lipid metabolism. There are five distinct perilipins (PLIN1–5),...

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Bibliographic Details
Main Authors: Victória Bombarda-Rocha, Dany Silva, Allal Badr-Eddine, Patrícia Nogueira, Jorge Gonçalves, Paula Fresco
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Cancers
Subjects:
perilipins
lipid droplets
cancer
obesity
Online Access:https://www.mdpi.com/2072-6694/15/15/4013

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