Caudal Regression Syndrome—A Narrative Review: An Orthopedic Point of View
Abnormalities in cellular differentiation during embryo-fetal period may lead to various malformations of the spine. Caudal regression syndrome (CRS) is a group of defects with premature growth/development termination of the vertebral column. CRS can be divided into three types: sirenomelia, complet...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-03-01
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| Series: | Children |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2227-9067/10/3/589 |
| _version_ | 1827750480182247424 |
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| author | Barbara Jasiewicz Wojciech Kacki |
| author_facet | Barbara Jasiewicz Wojciech Kacki |
| author_sort | Barbara Jasiewicz |
| collection | DOAJ |
| description | Abnormalities in cellular differentiation during embryo-fetal period may lead to various malformations of the spine. Caudal regression syndrome (CRS) is a group of defects with premature growth/development termination of the vertebral column. CRS can be divided into three types: sirenomelia, complete absence of the sacrum and partial absence of the sacrum. Genitourinary and gastrointestinal anomalies are common, with neurogenic bladder and bowel incontinence. Treatment of patients with CRS is complex and multidisciplinary and should be comprehensive. The most common orthopedic problems are: spinal deformity (kyphosis and scoliosis), spinopelvic instability and lower limbs deformities. |
| first_indexed | 2024-03-11T06:43:42Z |
| format | Article |
| id | doaj.art-5cb4c2e241e842bd80aa3f088cc1bdbf |
| institution | Directory Open Access Journal |
| issn | 2227-9067 |
| language | English |
| last_indexed | 2024-03-11T06:43:42Z |
| publishDate | 2023-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Children |
| spelling | doaj.art-5cb4c2e241e842bd80aa3f088cc1bdbf2023-11-17T10:22:24ZengMDPI AGChildren2227-90672023-03-0110358910.3390/children10030589Caudal Regression Syndrome—A Narrative Review: An Orthopedic Point of ViewBarbara Jasiewicz0Wojciech Kacki1Department of Orthopedics and Rehabilitation, Jagiellonian University Collegium Medicum, Balzera 15, 34-500 Zakopane, PolandDepartment of Orthopedics and Rehabilitation, Jagiellonian University Collegium Medicum, Balzera 15, 34-500 Zakopane, PolandAbnormalities in cellular differentiation during embryo-fetal period may lead to various malformations of the spine. Caudal regression syndrome (CRS) is a group of defects with premature growth/development termination of the vertebral column. CRS can be divided into three types: sirenomelia, complete absence of the sacrum and partial absence of the sacrum. Genitourinary and gastrointestinal anomalies are common, with neurogenic bladder and bowel incontinence. Treatment of patients with CRS is complex and multidisciplinary and should be comprehensive. The most common orthopedic problems are: spinal deformity (kyphosis and scoliosis), spinopelvic instability and lower limbs deformities.https://www.mdpi.com/2227-9067/10/3/589caudal regression syndromesacral agenesispediatric spine |
| spellingShingle | Barbara Jasiewicz Wojciech Kacki Caudal Regression Syndrome—A Narrative Review: An Orthopedic Point of View Children caudal regression syndrome sacral agenesis pediatric spine |
| title | Caudal Regression Syndrome—A Narrative Review: An Orthopedic Point of View |
| title_full | Caudal Regression Syndrome—A Narrative Review: An Orthopedic Point of View |
| title_fullStr | Caudal Regression Syndrome—A Narrative Review: An Orthopedic Point of View |
| title_full_unstemmed | Caudal Regression Syndrome—A Narrative Review: An Orthopedic Point of View |
| title_short | Caudal Regression Syndrome—A Narrative Review: An Orthopedic Point of View |
| title_sort | caudal regression syndrome a narrative review an orthopedic point of view |
| topic | caudal regression syndrome sacral agenesis pediatric spine |
| url | https://www.mdpi.com/2227-9067/10/3/589 |
| work_keys_str_mv | AT barbarajasiewicz caudalregressionsyndromeanarrativereviewanorthopedicpointofview AT wojciechkacki caudalregressionsyndromeanarrativereviewanorthopedicpointofview |