Synthesis, Structure–Activity Relationships, and Parasitological Profiling of Brussonol Derivatives as New <i>Plasmodium</i> <i>falciparum</i> Inhibitors

Synthesis, Structure–Activity Relationships, and Parasitological Profiling of Brussonol Derivatives as New <i>Plasmodium</i> <i>falciparum</i> Inhibitors

Malaria is a parasitic disease caused by protozoan parasites from the genus <i>Plasmodium</i>. <i>Plasmodium falciparum</i> is the most prevalent species worldwide and the causative agent of severe malaria. The spread of resistance to the currently available antimalarial ther...

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Bibliographic Details
Main Authors: Camila S. Barbosa, Anees Ahmad, Sarah El Chamy Maluf, Igor M. R. Moura, Guilherme E. Souza, Giovanna A. H. Guerra, Roberto R. Moraes Barros, Marcos L. Gazarini, Anna C. C. Aguiar, Antonio C. B. Burtoloso, Rafael V. C. Guido
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Pharmaceuticals
Subjects:
malaria
icetexane diterpenoids
antimalarials
resistance
<i>Plasmodium</i> <i>falciparum</i>
Online Access:https://www.mdpi.com/1424-8247/15/7/814

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