Effect of percutaneous transluminal coronary angioplasty in patients with chronic occlusion of right coronary artery on clinical characteristics and stress MRI indicators in postoperative period

<p>Objective. In the last few years CTO angioplasty technique has shown high rates of procedural success and low rates of complications, but benefits from CTO recanalization are still not clear. In this report, the authors try to evaluate the effectiveness of CTO recanalization and discuss the...

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Main Authors: А. А. Обединский, В. П. Курбатов, Н. Р. Обединская, В. В. Верин, Е. И. Кретов, Д. Н. Пономарев, Е. А. Покушалов
Format: Article
Language:English
Published: Meshalkin National Medical Research Center 2016-01-01
Series:Патология кровообращения и кардиохирургия
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Online Access:http://journalmeshalkin.ru/index.php/heartjournal/article/view/265
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author А. А. Обединский
В. П. Курбатов
Н. Р. Обединская
В. В. Верин
Е. И. Кретов
Д. Н. Пономарев
Е. А. Покушалов
author_facet А. А. Обединский
В. П. Курбатов
Н. Р. Обединская
В. В. Верин
Е. И. Кретов
Д. Н. Пономарев
Е. А. Покушалов
author_sort А. А. Обединский
collection DOAJ
description <p>Objective. In the last few years CTO angioplasty technique has shown high rates of procedural success and low rates of complications, but benefits from CTO recanalization are still not clear. In this report, the authors try to evaluate the effectiveness of CTO recanalization and discuss the diagnostic tool that might improve the appropriateness of CTO percutaneous coronary intervention.<br />Methods. We examined and treated 72 patients, with 39 patients undergoing CTO-PCI of the right coronary artery (Group 1) and 33 receiving medical therapy only (Group 2). The perfusion areas of the CTO vessel and the clinical status of patients were evaluated. The follow-up period was 2 and 12 months. <br />Results. According to stress MRI data, throughout the study, patients who underwent RCA stenting had a significantly higher risk of reducing the functional class of heart failure, the best performance at 6-min treadmill test and a low class of angina (below III), as well as a decreased number of perfusion defect points (less than 5) as compared with those of the control group (p&lt;0.001). In addition, the quality of life of patients in the intervention group consistently exceeded that in the control group.<br />Conclusion. CTO recanalization as compared to medical therapy only noticeably improves clinical outcomes of isolated CTO. Our findings correlate with stress MRI results.</p>
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spelling doaj.art-5cb6191877ce4f42b50560797614a8242023-08-02T00:42:58ZengMeshalkin National Medical Research CenterПатология кровообращения и кардиохирургия1681-34722500-31192016-01-01194485310.21688/1681-3472-2015-4-48-53977Effect of percutaneous transluminal coronary angioplasty in patients with chronic occlusion of right coronary artery on clinical characteristics and stress MRI indicators in postoperative periodА. А. Обединский0В. П. Курбатов1Н. Р. Обединская2В. В. Верин3Е. И. Кретов4Д. Н. Пономарев5Е. А. Покушалов6Новосибирский научно-исследовательский институт имени академика Е.Н. Мешалкина Министерства здравоохранения Российской Федерации, 630055, Новосибирск, ул. Речкуновская, 15Новосибирский научно-исследовательский институт имени академика Е.Н. Мешалкина Министерства здравоохранения Российской Федерации, 630055, Новосибирск, ул. Речкуновская, 15Новосибирский научно-исследовательский институт имени академика Е.Н. Мешалкина Министерства здравоохранения Российской Федерации, 630055, Новосибирск, ул. Речкуновская, 15Приморская краевая клиническая больница № 1, 690091, Владивосток, ул. Алеутская, 57Новосибирский научно-исследовательский институт имени академика Е.Н. Мешалкина Министерства здравоохранения Российской Федерации, 630055, Новосибирск, ул. Речкуновская, 15Новосибирский научно-исследовательский институт имени академика Е.Н. Мешалкина Министерства здравоохранения Российской Федерации, 630055, Новосибирск, ул. Речкуновская, 15Новосибирский научно-исследовательский институт имени академика Е.Н. Мешалкина Министерства здравоохранения Российской Федерации, 630055, Новосибирск, ул. Речкуновская, 15<p>Objective. In the last few years CTO angioplasty technique has shown high rates of procedural success and low rates of complications, but benefits from CTO recanalization are still not clear. In this report, the authors try to evaluate the effectiveness of CTO recanalization and discuss the diagnostic tool that might improve the appropriateness of CTO percutaneous coronary intervention.<br />Methods. We examined and treated 72 patients, with 39 patients undergoing CTO-PCI of the right coronary artery (Group 1) and 33 receiving medical therapy only (Group 2). The perfusion areas of the CTO vessel and the clinical status of patients were evaluated. The follow-up period was 2 and 12 months. <br />Results. According to stress MRI data, throughout the study, patients who underwent RCA stenting had a significantly higher risk of reducing the functional class of heart failure, the best performance at 6-min treadmill test and a low class of angina (below III), as well as a decreased number of perfusion defect points (less than 5) as compared with those of the control group (p&lt;0.001). In addition, the quality of life of patients in the intervention group consistently exceeded that in the control group.<br />Conclusion. CTO recanalization as compared to medical therapy only noticeably improves clinical outcomes of isolated CTO. Our findings correlate with stress MRI results.</p>http://journalmeshalkin.ru/index.php/heartjournal/article/view/265Хроническая окклюзияРеканализацияКонсервативная терапияКлинические характеристикиСтресс-МРТ
spellingShingle А. А. Обединский
В. П. Курбатов
Н. Р. Обединская
В. В. Верин
Е. И. Кретов
Д. Н. Пономарев
Е. А. Покушалов
Effect of percutaneous transluminal coronary angioplasty in patients with chronic occlusion of right coronary artery on clinical characteristics and stress MRI indicators in postoperative period
Патология кровообращения и кардиохирургия
Хроническая окклюзия
Реканализация
Консервативная терапия
Клинические характеристики
Стресс-МРТ
title Effect of percutaneous transluminal coronary angioplasty in patients with chronic occlusion of right coronary artery on clinical characteristics and stress MRI indicators in postoperative period
title_full Effect of percutaneous transluminal coronary angioplasty in patients with chronic occlusion of right coronary artery on clinical characteristics and stress MRI indicators in postoperative period
title_fullStr Effect of percutaneous transluminal coronary angioplasty in patients with chronic occlusion of right coronary artery on clinical characteristics and stress MRI indicators in postoperative period
title_full_unstemmed Effect of percutaneous transluminal coronary angioplasty in patients with chronic occlusion of right coronary artery on clinical characteristics and stress MRI indicators in postoperative period
title_short Effect of percutaneous transluminal coronary angioplasty in patients with chronic occlusion of right coronary artery on clinical characteristics and stress MRI indicators in postoperative period
title_sort effect of percutaneous transluminal coronary angioplasty in patients with chronic occlusion of right coronary artery on clinical characteristics and stress mri indicators in postoperative period
topic Хроническая окклюзия
Реканализация
Консервативная терапия
Клинические характеристики
Стресс-МРТ
url http://journalmeshalkin.ru/index.php/heartjournal/article/view/265
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