Contribution of climate and air pollution to variation in coronary heart disease mortality rates in England.
There are substantial geographic variations in coronary heart disease (CHD) mortality rates in England that may in part be due to differences in climate and air pollution. An ecological cross-sectional multi-level analysis of male and female CHD mortality rates in all wards in England (1999-2004) wa...
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Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3299689?pdf=render |
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author | Peter Scarborough Steven Allender Mike Rayner Michael Goldacre |
author_facet | Peter Scarborough Steven Allender Mike Rayner Michael Goldacre |
author_sort | Peter Scarborough |
collection | DOAJ |
description | There are substantial geographic variations in coronary heart disease (CHD) mortality rates in England that may in part be due to differences in climate and air pollution. An ecological cross-sectional multi-level analysis of male and female CHD mortality rates in all wards in England (1999-2004) was conducted to estimate the relative strength of the association between CHD mortality rates and three aspects of the physical environment--temperature, hours of sunshine and air quality. Models were adjusted for deprivation, an index measuring the healthiness of the lifestyle of populations, and urbanicity. In the fully adjusted model, air quality was not significantly associated with CHD mortality rates, but temperature and sunshine were both significantly negatively associated (p<0.05), suggesting that CHD mortality rates were higher in areas with lower average temperature and hours of sunshine. After adjustment for the unhealthy lifestyle of populations and deprivation, the climate variables explained at least 15% of large scale variation in CHD mortality rates. The results suggest that the climate has a small but significant independent association with CHD mortality rates in England. |
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spelling | doaj.art-5cb7f46980e84ce2b29d28b023bf4e212022-12-22T03:07:43ZengPublic Library of Science (PLoS)PLoS ONE1932-62032012-01-0173e3278710.1371/journal.pone.0032787Contribution of climate and air pollution to variation in coronary heart disease mortality rates in England.Peter ScarboroughSteven AllenderMike RaynerMichael GoldacreThere are substantial geographic variations in coronary heart disease (CHD) mortality rates in England that may in part be due to differences in climate and air pollution. An ecological cross-sectional multi-level analysis of male and female CHD mortality rates in all wards in England (1999-2004) was conducted to estimate the relative strength of the association between CHD mortality rates and three aspects of the physical environment--temperature, hours of sunshine and air quality. Models were adjusted for deprivation, an index measuring the healthiness of the lifestyle of populations, and urbanicity. In the fully adjusted model, air quality was not significantly associated with CHD mortality rates, but temperature and sunshine were both significantly negatively associated (p<0.05), suggesting that CHD mortality rates were higher in areas with lower average temperature and hours of sunshine. After adjustment for the unhealthy lifestyle of populations and deprivation, the climate variables explained at least 15% of large scale variation in CHD mortality rates. The results suggest that the climate has a small but significant independent association with CHD mortality rates in England.http://europepmc.org/articles/PMC3299689?pdf=render |
spellingShingle | Peter Scarborough Steven Allender Mike Rayner Michael Goldacre Contribution of climate and air pollution to variation in coronary heart disease mortality rates in England. PLoS ONE |
title | Contribution of climate and air pollution to variation in coronary heart disease mortality rates in England. |
title_full | Contribution of climate and air pollution to variation in coronary heart disease mortality rates in England. |
title_fullStr | Contribution of climate and air pollution to variation in coronary heart disease mortality rates in England. |
title_full_unstemmed | Contribution of climate and air pollution to variation in coronary heart disease mortality rates in England. |
title_short | Contribution of climate and air pollution to variation in coronary heart disease mortality rates in England. |
title_sort | contribution of climate and air pollution to variation in coronary heart disease mortality rates in england |
url | http://europepmc.org/articles/PMC3299689?pdf=render |
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