Contribution of climate and air pollution to variation in coronary heart disease mortality rates in England.

There are substantial geographic variations in coronary heart disease (CHD) mortality rates in England that may in part be due to differences in climate and air pollution. An ecological cross-sectional multi-level analysis of male and female CHD mortality rates in all wards in England (1999-2004) wa...

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Main Authors: Peter Scarborough, Steven Allender, Mike Rayner, Michael Goldacre
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3299689?pdf=render
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author Peter Scarborough
Steven Allender
Mike Rayner
Michael Goldacre
author_facet Peter Scarborough
Steven Allender
Mike Rayner
Michael Goldacre
author_sort Peter Scarborough
collection DOAJ
description There are substantial geographic variations in coronary heart disease (CHD) mortality rates in England that may in part be due to differences in climate and air pollution. An ecological cross-sectional multi-level analysis of male and female CHD mortality rates in all wards in England (1999-2004) was conducted to estimate the relative strength of the association between CHD mortality rates and three aspects of the physical environment--temperature, hours of sunshine and air quality. Models were adjusted for deprivation, an index measuring the healthiness of the lifestyle of populations, and urbanicity. In the fully adjusted model, air quality was not significantly associated with CHD mortality rates, but temperature and sunshine were both significantly negatively associated (p<0.05), suggesting that CHD mortality rates were higher in areas with lower average temperature and hours of sunshine. After adjustment for the unhealthy lifestyle of populations and deprivation, the climate variables explained at least 15% of large scale variation in CHD mortality rates. The results suggest that the climate has a small but significant independent association with CHD mortality rates in England.
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spelling doaj.art-5cb7f46980e84ce2b29d28b023bf4e212022-12-22T03:07:43ZengPublic Library of Science (PLoS)PLoS ONE1932-62032012-01-0173e3278710.1371/journal.pone.0032787Contribution of climate and air pollution to variation in coronary heart disease mortality rates in England.Peter ScarboroughSteven AllenderMike RaynerMichael GoldacreThere are substantial geographic variations in coronary heart disease (CHD) mortality rates in England that may in part be due to differences in climate and air pollution. An ecological cross-sectional multi-level analysis of male and female CHD mortality rates in all wards in England (1999-2004) was conducted to estimate the relative strength of the association between CHD mortality rates and three aspects of the physical environment--temperature, hours of sunshine and air quality. Models were adjusted for deprivation, an index measuring the healthiness of the lifestyle of populations, and urbanicity. In the fully adjusted model, air quality was not significantly associated with CHD mortality rates, but temperature and sunshine were both significantly negatively associated (p<0.05), suggesting that CHD mortality rates were higher in areas with lower average temperature and hours of sunshine. After adjustment for the unhealthy lifestyle of populations and deprivation, the climate variables explained at least 15% of large scale variation in CHD mortality rates. The results suggest that the climate has a small but significant independent association with CHD mortality rates in England.http://europepmc.org/articles/PMC3299689?pdf=render
spellingShingle Peter Scarborough
Steven Allender
Mike Rayner
Michael Goldacre
Contribution of climate and air pollution to variation in coronary heart disease mortality rates in England.
PLoS ONE
title Contribution of climate and air pollution to variation in coronary heart disease mortality rates in England.
title_full Contribution of climate and air pollution to variation in coronary heart disease mortality rates in England.
title_fullStr Contribution of climate and air pollution to variation in coronary heart disease mortality rates in England.
title_full_unstemmed Contribution of climate and air pollution to variation in coronary heart disease mortality rates in England.
title_short Contribution of climate and air pollution to variation in coronary heart disease mortality rates in England.
title_sort contribution of climate and air pollution to variation in coronary heart disease mortality rates in england
url http://europepmc.org/articles/PMC3299689?pdf=render
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