Effect of Exercise Training on Gene Expression of Adiponectin and its Receptors in Testicles and Sex Hormones in Diabetic Rats
Adiponectin and its receptors are expressed in the male reproductive system, which play a role in regulating male sex hormones and fertility. Diabetes was induced by Streptozotocin-Nicotinamide (STZ-NA i.p) in rats and after performing the trainings, adiponectin gene expression and its receptors in...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2021-02-01
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| Series: | Journal of Biological Research |
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| Online Access: | https://pagepressjournals.org/index.php/jbr/article/view/9287 |
| _version_ | 1818864553195208704 |
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| author | Zahra Nadi Mohammad Bayat Hadi Karami Mohamad Parastesh ParvinDokht Bayat |
| author_facet | Zahra Nadi Mohammad Bayat Hadi Karami Mohamad Parastesh ParvinDokht Bayat |
| author_sort | Zahra Nadi |
| collection | DOAJ |
| description | Adiponectin and its receptors are expressed in the male reproductive system, which play a role in regulating male sex hormones and fertility. Diabetes was induced by Streptozotocin-Nicotinamide (STZ-NA i.p) in rats and after performing the trainings, adiponectin gene expression and its receptors in the testis were evaluated using real time PCR, and blood serum was then used in order to assess FSH, LH and testosterone. The STZ-NA significantly increased the fasting blood glucose, gene expression of adiponectin AdipoR1 in the testicles of diabetic rats. A significant reduction in serum testosterone and LH levels were observed in the diabetic group. Resistance and endurance training decreased blood glucose, adiponectin and AdipoR1 gene, and also increased the serum testosterone and LH levels in diabetic rats. Overall, our data suggest the role played by training in improve expression of adiponectin and AdipoR1 gene by increasing the serum testosterone and LH levels in type 2 diabetic rats. |
| first_indexed | 2024-12-19T10:33:29Z |
| format | Article |
| id | doaj.art-5cbaceb6540f423dac47291ce945bb46 |
| institution | Directory Open Access Journal |
| issn | 1826-8838 2284-0230 |
| language | English |
| last_indexed | 2024-12-19T10:33:29Z |
| publishDate | 2021-02-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Journal of Biological Research |
| spelling | doaj.art-5cbaceb6540f423dac47291ce945bb462022-12-21T20:25:41ZengPAGEPress PublicationsJournal of Biological Research1826-88382284-02302021-02-0110.4081/jbr.0.9287Effect of Exercise Training on Gene Expression of Adiponectin and its Receptors in Testicles and Sex Hormones in Diabetic RatsZahra Nadi0Mohammad Bayat1Hadi Karami2Mohamad Parastesh3ParvinDokht Bayat4Department of Anatomy, School of MedicineDepartment of Anatomy, School of MedicineDepartment of Molecular Medicine and Biotechnology, Faculty of MedicineDepartment of Sport Physiology, Faculty of Sport Sciences, Arak University, ArakDepartment of Anatomy, School of MedicineAdiponectin and its receptors are expressed in the male reproductive system, which play a role in regulating male sex hormones and fertility. Diabetes was induced by Streptozotocin-Nicotinamide (STZ-NA i.p) in rats and after performing the trainings, adiponectin gene expression and its receptors in the testis were evaluated using real time PCR, and blood serum was then used in order to assess FSH, LH and testosterone. The STZ-NA significantly increased the fasting blood glucose, gene expression of adiponectin AdipoR1 in the testicles of diabetic rats. A significant reduction in serum testosterone and LH levels were observed in the diabetic group. Resistance and endurance training decreased blood glucose, adiponectin and AdipoR1 gene, and also increased the serum testosterone and LH levels in diabetic rats. Overall, our data suggest the role played by training in improve expression of adiponectin and AdipoR1 gene by increasing the serum testosterone and LH levels in type 2 diabetic rats.https://pagepressjournals.org/index.php/jbr/article/view/9287DiabetesAdiponectinAdipoR1 and AdipoR2Sex hormonesTraining |
| spellingShingle | Zahra Nadi Mohammad Bayat Hadi Karami Mohamad Parastesh ParvinDokht Bayat Effect of Exercise Training on Gene Expression of Adiponectin and its Receptors in Testicles and Sex Hormones in Diabetic Rats Journal of Biological Research Diabetes Adiponectin AdipoR1 and AdipoR2 Sex hormones Training |
| title | Effect of Exercise Training on Gene Expression of Adiponectin and its Receptors in Testicles and Sex Hormones in Diabetic Rats |
| title_full | Effect of Exercise Training on Gene Expression of Adiponectin and its Receptors in Testicles and Sex Hormones in Diabetic Rats |
| title_fullStr | Effect of Exercise Training on Gene Expression of Adiponectin and its Receptors in Testicles and Sex Hormones in Diabetic Rats |
| title_full_unstemmed | Effect of Exercise Training on Gene Expression of Adiponectin and its Receptors in Testicles and Sex Hormones in Diabetic Rats |
| title_short | Effect of Exercise Training on Gene Expression of Adiponectin and its Receptors in Testicles and Sex Hormones in Diabetic Rats |
| title_sort | effect of exercise training on gene expression of adiponectin and its receptors in testicles and sex hormones in diabetic rats |
| topic | Diabetes Adiponectin AdipoR1 and AdipoR2 Sex hormones Training |
| url | https://pagepressjournals.org/index.php/jbr/article/view/9287 |
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