Long noncoding RNA FTX ameliorates hydrogen peroxide-induced cardiomyocyte injury by regulating the miR-150/KLF13 axis
Myocardial reperfusion is an effective therapy for acute myocardial infarction (AMI). However, ischemia/reperfusion (I/R) injury following myocardial reperfusion is a significant limitation for AMI treatment. Five prime to Xist (FTX) was recognized as a biomarker of multiple diseases, including hear...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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De Gruyter
2020-12-01
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| Series: | Open Life Sciences |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/biol-2020-0100 |
| _version_ | 1819116033398538240 |
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| author | Zhang Yamin Fan Xiaoying Yang Hua |
| author_facet | Zhang Yamin Fan Xiaoying Yang Hua |
| author_sort | Zhang Yamin |
| collection | DOAJ |
| description | Myocardial reperfusion is an effective therapy for acute myocardial infarction (AMI). However, ischemia/reperfusion (I/R) injury following myocardial reperfusion is a significant limitation for AMI treatment. Five prime to Xist (FTX) was recognized as a biomarker of multiple diseases, including heart disease. However, the molecular mechanism of FTX in I/R injury is unclear. |
| first_indexed | 2024-12-22T05:10:39Z |
| format | Article |
| id | doaj.art-5cbb4ad79e624a1aa060ad4709253b01 |
| institution | Directory Open Access Journal |
| issn | 2391-5412 |
| language | English |
| last_indexed | 2024-12-22T05:10:39Z |
| publishDate | 2020-12-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Open Life Sciences |
| spelling | doaj.art-5cbb4ad79e624a1aa060ad4709253b012022-12-21T18:38:00ZengDe GruyterOpen Life Sciences2391-54122020-12-011511000101210.1515/biol-2020-0100biol-2020-0100Long noncoding RNA FTX ameliorates hydrogen peroxide-induced cardiomyocyte injury by regulating the miR-150/KLF13 axisZhang Yamin0Fan Xiaoying1Yang Hua2Department of Cardiology, The First Affiliated Hospital of Airforce Military Medical University, No. 127, Changle West Road, Xi’an, Shaanxi, 710032, ChinaDepartment of Cardiology, The First Affiliated Hospital of Airforce Military Medical University, No. 127, Changle West Road, Xi’an, Shaanxi, 710032, ChinaDepartment of Cardiology, The First Affiliated Hospital of Airforce Military Medical University, No. 127, Changle West Road, Xi’an, Shaanxi, 710032, ChinaMyocardial reperfusion is an effective therapy for acute myocardial infarction (AMI). However, ischemia/reperfusion (I/R) injury following myocardial reperfusion is a significant limitation for AMI treatment. Five prime to Xist (FTX) was recognized as a biomarker of multiple diseases, including heart disease. However, the molecular mechanism of FTX in I/R injury is unclear.https://doi.org/10.1515/biol-2020-0100i/r injurylnc ftxmir-150klf13progression |
| spellingShingle | Zhang Yamin Fan Xiaoying Yang Hua Long noncoding RNA FTX ameliorates hydrogen peroxide-induced cardiomyocyte injury by regulating the miR-150/KLF13 axis Open Life Sciences i/r injury lnc ftx mir-150 klf13 progression |
| title | Long noncoding RNA FTX ameliorates hydrogen peroxide-induced cardiomyocyte injury by regulating the miR-150/KLF13 axis |
| title_full | Long noncoding RNA FTX ameliorates hydrogen peroxide-induced cardiomyocyte injury by regulating the miR-150/KLF13 axis |
| title_fullStr | Long noncoding RNA FTX ameliorates hydrogen peroxide-induced cardiomyocyte injury by regulating the miR-150/KLF13 axis |
| title_full_unstemmed | Long noncoding RNA FTX ameliorates hydrogen peroxide-induced cardiomyocyte injury by regulating the miR-150/KLF13 axis |
| title_short | Long noncoding RNA FTX ameliorates hydrogen peroxide-induced cardiomyocyte injury by regulating the miR-150/KLF13 axis |
| title_sort | long noncoding rna ftx ameliorates hydrogen peroxide induced cardiomyocyte injury by regulating the mir 150 klf13 axis |
| topic | i/r injury lnc ftx mir-150 klf13 progression |
| url | https://doi.org/10.1515/biol-2020-0100 |
| work_keys_str_mv | AT zhangyamin longnoncodingrnaftxameliorateshydrogenperoxideinducedcardiomyocyteinjurybyregulatingthemir150klf13axis AT fanxiaoying longnoncodingrnaftxameliorateshydrogenperoxideinducedcardiomyocyteinjurybyregulatingthemir150klf13axis AT yanghua longnoncodingrnaftxameliorateshydrogenperoxideinducedcardiomyocyteinjurybyregulatingthemir150klf13axis |