C/EBPβ mediates NQO1 and GSTP1 anti-oxidative reductases expression in glioblastoma, promoting brain tumor proliferation

C/EBPβ mediates NQO1 and GSTP1 anti-oxidative reductases expression in glioblastoma, promoting brain tumor proliferation

Glioblastoma (GBM) is the most common and most aggressive brain tumor, associated with high levels of reactive oxidative species (ROS) due to metabolic and signaling aberrations. High ROS levels are detrimental to cells, but it remains incompletely understood how cancer cells cope with the adverse e...

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Bibliographic Details
Main Authors: Kecheng Lei, Yiyuan Xia, Xiao-Chuan Wang, Eun Hee Ahn, Lingjing Jin, Keqiang Ye
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Redox Biology
Subjects:
Oxidative stress
NQO1
GSTP1
Transcription factor
C/EBPβ
GBM
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231720306376

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