Structural basis for Scc3-dependent cohesin recruitment to chromatin

Structural basis for Scc3-dependent cohesin recruitment to chromatin

The cohesin ring complex is required for numerous chromosomal transactions including sister chromatid cohesion, DNA damage repair and transcriptional regulation. How cohesin engages its chromatin substrate has remained an unresolved question. We show here, by determining a crystal structure of the b...

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Bibliographic Details
Main Authors: Yan Li, Kyle W Muir, Matthew W Bowler, Jutta Metz, Christian H Haering, Daniel Panne
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-08-01
Series:eLife
Subjects:
cohesin
cell proliferation
Scc3
DNA binding
Online Access:https://elifesciences.org/articles/38356

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