Summary: | The basis of the mechanism of cilia and sperm flagella motility is the sliding of doublets of microtubules relative to each other due to translational movement of dyneins. Previously, external and internal dynein arm were considered similar in structure and functions, however, recent experimental data suggest a significant difference in the composition of subunits, axoneme location, and regulatory mechanisms. And although the understanding of the principles of changes in the activity of the described motor proteins remains incomplete, subtle mechanisms of the functioning of these structures have been established.
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