Formyl-methionine as a degradation signal at the N-termini of bacterial proteins
In bacteria, all nascent proteins bear the pretranslationally formed N-terminal formyl-methionine (fMet) residue. The fMet residue is cotranslationally deformylated by a ribosome-associated deformylase. The formylation of N-terminal Met in bacterial proteins is not strictly essential for either tran...
Main Authors: | Konstantin I. Piatkov, Tri T. M. Vu, Cheol-Sang Hwang, Alexander Varshavsky |
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Format: | Article |
Language: | English |
Published: |
Shared Science Publishers OG
2015-09-01
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Series: | Microbial Cell |
Subjects: | |
Online Access: | http://microbialcell.com/researcharticles/formyl-methionine-as-a-degradation-signal-at-the-n-termini-of-bacterial-proteins/ |
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