Improved early development of porcine cloned embryos by treatment with quisinostat, a potent histone deacetylase inhibitor

Improved early development of porcine cloned embryos by treatment with quisinostat, a potent histone deacetylase inhibitor

Recently, the modification of the epigenetic status of somatic cell nuclear transfer (SCNT) embryos by treatment with histone deacetylase inhibitors (HDACis) has made it possible to alter epigenetic traits and improve the developmental competence of these embryos. In the current study, we examined t...

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Bibliographic Details
Main Authors: Anukul TAWEECHAIPAISANKUL, Jun-Xue JIN, Sanghoon LEE, Geon A KIM, Yoon Ho SUH, Min Seok AHN, Se Jun PARK, Byeong You LEE, Byeong Chun LEE
Format: Article
Language:English
Published: The Society for Reproduction and Development 2018-12-01
Series:The Journal of Reproduction and Development
Subjects:
histone deacetylase inhibitor
porcine in vitro culture
quisinostat
somatic cell nuclear transfer
Online Access:https://www.jstage.jst.go.jp/article/jrd/65/2/65_2018-098/_pdf/-char/en

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