Structural analysis of receptor engagement and antigenic drift within the BA.2 spike protein

Structural analysis of receptor engagement and antigenic drift within the BA.2 spike protein

Summary: The BA.2 sub-lineage of the Omicron (B.1.1.529) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant rapidly supplanted the original BA.1 sub-lineage in early 2022. Both lineages threatened the efficacy of vaccine-elicited antibodies and acquired increased binding to several...

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Bibliographic Details
Main Authors: James W. Saville, Dhiraj Mannar, Xing Zhu, Alison M. Berezuk, Spencer Cholak, Katherine S. Tuttle, Faezeh Vahdatihassani, Sriram Subramaniam
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Cell Reports
Subjects:
CP: Immunology
CP: Molecular biology
Online Access:http://www.sciencedirect.com/science/article/pii/S221112472201868X

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