The association of painful and non-painful morbidities with frailty: a cross sectional analysis of a cohort of community dwelling older people in England
Abstract Introduction The association between chronic pain and frailty might indicate that pain is an independent driver of frailty but might alternatively be explained by inclusion within frailty identification tools of morbidities that commonly lead to chronic pain. This research examines the exte...
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| Format: | Article |
| Language: | English |
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BMC
2024-02-01
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| Series: | BMC Geriatrics |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12877-023-04602-w |
| _version_ | 1827326314760110080 |
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| author | W. J. Chaplin H. R. Lewis S. M. Shahtaheri B. S. Millar D. F. McWilliams J. R. F. Gladman D. A. Walsh |
| author_facet | W. J. Chaplin H. R. Lewis S. M. Shahtaheri B. S. Millar D. F. McWilliams J. R. F. Gladman D. A. Walsh |
| author_sort | W. J. Chaplin |
| collection | DOAJ |
| description | Abstract Introduction The association between chronic pain and frailty might indicate that pain is an independent driver of frailty but might alternatively be explained by inclusion within frailty identification tools of morbidities that commonly lead to chronic pain. This research examines the extent to which the association of pain with frailty might be attributed to morbidities. Methods A cross-sectional analysis of older people in a UK cohort with or at risk of musculoskeletal problems or frailty (Investigating Musculoskeletal Health and Wellbeing study), used multivariable logistic regression and Z-tests to assess the degrees of associations of pain (McGill Pain Rating Index), and painful and non-painful morbidity counts with frailty (modified FRAIL questionnaire). Results Data were from 2,185 participants, 56% female, median age 73 (range 60 to 96) years. 430 (20%) participants were classified as frail. In a fully adjusted standardised model, pain (aOR 2.07 (95%CI 1.83 to 2.33) and ‘any’ morbidity aOR (1.74 (95%CI 1.54 to 1.97) were both significantly associated with frailty. When morbidity was subclassified as painful or non-painful, painful (aOR 1.48 (95%CI 1.30 to 1.68) and non-painful (aOR1.39 (95%CI 1.24 to 1.56)) morbidities each were associated with frailty, as also was pain (aOR 2.07 (95%CI 1.83 to 2.34, p < 0.001). Conclusions Pain is associated with frailty, over and above any effect of painful and non-painful morbidities. This forms the justification for future research which focuses on pain management in the identification, prevention, and treatment of frailty. |
| first_indexed | 2024-03-07T14:42:38Z |
| format | Article |
| id | doaj.art-5cceb0030b0e47908bf12d7cdac556f9 |
| institution | Directory Open Access Journal |
| issn | 1471-2318 |
| language | English |
| last_indexed | 2024-03-07T14:42:38Z |
| publishDate | 2024-02-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Geriatrics |
| spelling | doaj.art-5cceb0030b0e47908bf12d7cdac556f92024-03-05T20:11:33ZengBMCBMC Geriatrics1471-23182024-02-012411910.1186/s12877-023-04602-wThe association of painful and non-painful morbidities with frailty: a cross sectional analysis of a cohort of community dwelling older people in EnglandW. J. Chaplin0H. R. Lewis1S. M. Shahtaheri2B. S. Millar3D. F. McWilliams4J. R. F. Gladman5D. A. Walsh6Academic Rheumatology, Injury, Recovery and Inflammation Sciences, University of NottinghamAcademic Rheumatology, Injury, Recovery and Inflammation Sciences, University of NottinghamAcademic Rheumatology, Injury, Recovery and Inflammation Sciences, University of NottinghamAcademic Rheumatology, Injury, Recovery and Inflammation Sciences, University of NottinghamAcademic Rheumatology, Injury, Recovery and Inflammation Sciences, University of NottinghamPain Centre Versus Arthritis, University of NottinghamAcademic Rheumatology, Injury, Recovery and Inflammation Sciences, University of NottinghamAbstract Introduction The association between chronic pain and frailty might indicate that pain is an independent driver of frailty but might alternatively be explained by inclusion within frailty identification tools of morbidities that commonly lead to chronic pain. This research examines the extent to which the association of pain with frailty might be attributed to morbidities. Methods A cross-sectional analysis of older people in a UK cohort with or at risk of musculoskeletal problems or frailty (Investigating Musculoskeletal Health and Wellbeing study), used multivariable logistic regression and Z-tests to assess the degrees of associations of pain (McGill Pain Rating Index), and painful and non-painful morbidity counts with frailty (modified FRAIL questionnaire). Results Data were from 2,185 participants, 56% female, median age 73 (range 60 to 96) years. 430 (20%) participants were classified as frail. In a fully adjusted standardised model, pain (aOR 2.07 (95%CI 1.83 to 2.33) and ‘any’ morbidity aOR (1.74 (95%CI 1.54 to 1.97) were both significantly associated with frailty. When morbidity was subclassified as painful or non-painful, painful (aOR 1.48 (95%CI 1.30 to 1.68) and non-painful (aOR1.39 (95%CI 1.24 to 1.56)) morbidities each were associated with frailty, as also was pain (aOR 2.07 (95%CI 1.83 to 2.34, p < 0.001). Conclusions Pain is associated with frailty, over and above any effect of painful and non-painful morbidities. This forms the justification for future research which focuses on pain management in the identification, prevention, and treatment of frailty.https://doi.org/10.1186/s12877-023-04602-wChronic painFrailtyOlder peopleMorbidities |
| spellingShingle | W. J. Chaplin H. R. Lewis S. M. Shahtaheri B. S. Millar D. F. McWilliams J. R. F. Gladman D. A. Walsh The association of painful and non-painful morbidities with frailty: a cross sectional analysis of a cohort of community dwelling older people in England BMC Geriatrics Chronic pain Frailty Older people Morbidities |
| title | The association of painful and non-painful morbidities with frailty: a cross sectional analysis of a cohort of community dwelling older people in England |
| title_full | The association of painful and non-painful morbidities with frailty: a cross sectional analysis of a cohort of community dwelling older people in England |
| title_fullStr | The association of painful and non-painful morbidities with frailty: a cross sectional analysis of a cohort of community dwelling older people in England |
| title_full_unstemmed | The association of painful and non-painful morbidities with frailty: a cross sectional analysis of a cohort of community dwelling older people in England |
| title_short | The association of painful and non-painful morbidities with frailty: a cross sectional analysis of a cohort of community dwelling older people in England |
| title_sort | association of painful and non painful morbidities with frailty a cross sectional analysis of a cohort of community dwelling older people in england |
| topic | Chronic pain Frailty Older people Morbidities |
| url | https://doi.org/10.1186/s12877-023-04602-w |
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