Alpha-fetoprotein predicts the treatment efficacy of immune checkpoint inhibitors for gastric cancer patients

Alpha-fetoprotein predicts the treatment efficacy of immune checkpoint inhibitors for gastric cancer patients

Abstract Background Immune checkpoint inhibitors (ICIs) are commonly used in conjunction with chemotherapy to improve treatment outcomes for patients with gastric cancer. Since AFP could influence immunity by both inhibiting natural killer (NK) cells and regulating negatively the function of dendrit...

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Bibliographic Details
Main Authors:	Jingjing Zhang, Lei Wang, Shasha Zhang, Ruijie Cao, Yufei Zhao, Yue Zhao, Yanrong Song, Zhanjun Guo
Format:	Article
Language:	English
Published:	BMC 2024-02-01
Series:	BMC Cancer
Subjects:	Gastric cancer Alpha-fetoprotein Immune checkpoint inhibitors Anti-PD-1 antibody Therapeutic efficacy
Online Access:	https://doi.org/10.1186/s12885-024-11999-z

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