Adenosine Overcomes Triple-Negative Breast Cancer Resistance to Platinum-Derived Chemotherapeutic Drugs

Adenosine Overcomes Triple-Negative Breast Cancer Resistance to Platinum-Derived Chemotherapeutic Drugs

Triple-negative breast cancer (TNBC), a poor survival cancer has high resistance to therapy, with low-drug efficacy. Adenosine is present in high concentrations in the tumor microenvironment. Recently, adenosine was found to sensitize ovarian cisplatin-resistant cancer. This work aims at addressing...

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Bibliographic Details
Main Authors: Ana Cerquido, Martin Vojtek, Olga Viegas, Patricia Dias-Pereira, Carmen Diniz
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Medical Sciences Forum
Subjects:
adenosine
P1-receptors
carboplatin
cisplatin
TNBC
cancer resistance
Online Access:https://www.mdpi.com/2673-9992/14/1/146

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