Effects of the Amino Acid Constituents of Microcystin Variants on Cytotoxicity to Primary Cultured Rat Hepatocytes

Effects of the Amino Acid Constituents of Microcystin Variants on Cytotoxicity to Primary Cultured Rat Hepatocytes

Microcystins, which are cyclic heptapeptides produced by some cyanobacterial species from algal blooms, strongly inhibit serine/threonine protein phosphatase and are known as hepatotoxins. Microcystins have many structural variations, yet insufficient information is available on the differences in t...

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Bibliographic Details
Main Authors: Kumiko Shimizu, Tomoharu Sano, Reiji Kubota, Norihiro Kobayashi, Maiko Tahara, Tomoko Obama, Naoki Sugimoto, Tetsuji Nishimura, Yoshiaki Ikarashi
Format: Article
Language:English
Published: MDPI AG 2013-12-01
Series:Toxins
Subjects:
microcystin
variants
cytotoxicity
primary cultured rat hepatocytes
environmental water
Online Access:http://www.mdpi.com/2072-6651/6/1/168

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http://www.mdpi.com/2072-6651/6/1/168

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