A systematic review of miRNAs as biomarkers for chemotherapy-induced cardiotoxicity in breast cancer patients reveals potentially clinically informative panels as well as key challenges in miRNA research

A systematic review of miRNAs as biomarkers for chemotherapy-induced cardiotoxicity in breast cancer patients reveals potentially clinically informative panels as well as key challenges in miRNA research

Abstract Breast cancer patients are at a particularly high risk of cardiotoxicity from chemotherapy having a detrimental effect on quality-of-life parameters and increasing the risk of mortality. Prognostic biomarkers would allow the management of therapies to mitigate the risks of cardiotoxicity in...

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Bibliographic Details
Main Authors: Cameron Brown, Michael Mantzaris, Elpiniki Nicolaou, Georgia Karanasiou, Elisavet Papageorgiou, Giuseppe Curigliano, Daniela Cardinale, Gerasimos Filippatos, Nikolaos Memos, Katerina K. Naka, Andri Papakostantinou, Paris Vogazianos, Erietta Ioulianou, Christos Shammas, Anastasia Constantinidou, Federica Tozzi, Dimitrios I. Fotiadis, Athos Antoniades
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Cardio-Oncology
Subjects:
miRNA
microRNA
Cardiotoxicity
Breast cancer
Chemotherapy
Anthracycline
Online Access:https://doi.org/10.1186/s40959-022-00142-1

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