Multifactorial Activation of NLRP3 Inflammasome: Relevance for a Precision Approach to Atherosclerotic Cardiovascular Risk and Disease

Multifactorial Activation of NLRP3 Inflammasome: Relevance for a Precision Approach to Atherosclerotic Cardiovascular Risk and Disease

Chronic low-grade inflammation, through the specific activation of the NACHT leucine-rich repeat- and PYD-containing (NLRP)3 inflammasome-interleukin (IL)-1β pathway, is an important contributor to the development of atherosclerotic cardiovascular disease (ASCVD), being triggered by intracellular ch...

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Bibliographic Details
Main Authors: Andrea Baragetti, Alberico Luigi Catapano, Paolo Magni
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
cardiovascular disease
atherosclerosis
NLRP3 inflammasome
low-grade inflammation
interleukin-1β
single nucleotide polymorphism
Online Access:https://www.mdpi.com/1422-0067/21/12/4459

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