Investigation of Functional Synergism of CENPF and FOXM1 Identifies POLD1 as Downstream Target in Hepatocellular Carcinoma

Investigation of Functional Synergism of CENPF and FOXM1 Identifies POLD1 as Downstream Target in Hepatocellular Carcinoma

BackgroundLines of evidence implicate CENPF and FOXM1 may have novel co-operative roles in driving hepatocellular carcinoma (HCC).ObjectiveWe investigated the clinicopathological correlation, functional characterization, molecular mechanism and translational significance of CENPF and FOXM1.MethodsWe...

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Bibliographic Details
Main Authors: Daniel Wai-Hung Ho, Wai-Ling Macrina Lam, Lo-Kong Chan, Irene Oi-Lin Ng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Medicine
Subjects:
CENPF
FOXM1
POLD1
liver cancer
HCC
functional synergism
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.860395/full

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