Biosensors and Diagnostics for Fungal Detection
Early detection is critical to the successful treatment of life-threatening infections caused by fungal pathogens, as late diagnosis of systemic infection almost always equates with a poor prognosis. The field of fungal diagnostics has some tests that are relatively simple, rapid to perform and are...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-12-01
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| Series: | Journal of Fungi |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2309-608X/6/4/349 |
| _version_ | 1797545373519052800 |
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| author | Khalil K. Hussain Dhara Malavia Elizabeth M. Johnson Jennifer Littlechild C. Peter Winlove Frank Vollmer Neil A. R. Gow |
| author_facet | Khalil K. Hussain Dhara Malavia Elizabeth M. Johnson Jennifer Littlechild C. Peter Winlove Frank Vollmer Neil A. R. Gow |
| author_sort | Khalil K. Hussain |
| collection | DOAJ |
| description | Early detection is critical to the successful treatment of life-threatening infections caused by fungal pathogens, as late diagnosis of systemic infection almost always equates with a poor prognosis. The field of fungal diagnostics has some tests that are relatively simple, rapid to perform and are potentially suitable at the point of care. However, there are also more complex high-technology methodologies that offer new opportunities regarding the scale and precision of fungal diagnosis, but may be more limited in their portability and affordability. Future developments in this field are increasingly incorporating new technologies provided by the use of new format biosensors. This overview provides a critical review of current fungal diagnostics and the development of new biophysical technologies that are being applied for selective new sensitive fungal biosensors to augment traditional diagnostic methodologies. |
| first_indexed | 2024-03-10T14:14:34Z |
| format | Article |
| id | doaj.art-5ce55215bbe44702ab9d91ab8adb161c |
| institution | Directory Open Access Journal |
| issn | 2309-608X |
| language | English |
| last_indexed | 2024-03-10T14:14:34Z |
| publishDate | 2020-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Fungi |
| spelling | doaj.art-5ce55215bbe44702ab9d91ab8adb161c2023-11-20T23:55:22ZengMDPI AGJournal of Fungi2309-608X2020-12-016434910.3390/jof6040349Biosensors and Diagnostics for Fungal DetectionKhalil K. Hussain0Dhara Malavia1Elizabeth M. Johnson2Jennifer Littlechild3C. Peter Winlove4Frank Vollmer5Neil A. R. Gow6Medical Research Council Centre for Medical Mycology, University of Exeter, Geoffrey Pope Building, Stocker Road, Exeter EX4 4QD, UKMedical Research Council Centre for Medical Mycology, University of Exeter, Geoffrey Pope Building, Stocker Road, Exeter EX4 4QD, UKMedical Research Council Centre for Medical Mycology, University of Exeter, Geoffrey Pope Building, Stocker Road, Exeter EX4 4QD, UKBiocatalysis Centre, University of Exeter, The Henry Wellcome Building for Biocatalysis, Stocker Road, Exeter EX4 4QD, UKDepartment of Physics and Astronomy, College of Engineering, Mathematics and Physical Sciences, University of Exeter, Exeter EX4 4QD, UKLiving Systems Institute, University of Exeter, Stocker Road, Exeter EX4 4QD, UKMedical Research Council Centre for Medical Mycology, University of Exeter, Geoffrey Pope Building, Stocker Road, Exeter EX4 4QD, UKEarly detection is critical to the successful treatment of life-threatening infections caused by fungal pathogens, as late diagnosis of systemic infection almost always equates with a poor prognosis. The field of fungal diagnostics has some tests that are relatively simple, rapid to perform and are potentially suitable at the point of care. However, there are also more complex high-technology methodologies that offer new opportunities regarding the scale and precision of fungal diagnosis, but may be more limited in their portability and affordability. Future developments in this field are increasingly incorporating new technologies provided by the use of new format biosensors. This overview provides a critical review of current fungal diagnostics and the development of new biophysical technologies that are being applied for selective new sensitive fungal biosensors to augment traditional diagnostic methodologies.https://www.mdpi.com/2309-608X/6/4/349biosensorsdiagnosticsmedical mycologyfungal biomarkerpoint-of-care devicesimmobilization |
| spellingShingle | Khalil K. Hussain Dhara Malavia Elizabeth M. Johnson Jennifer Littlechild C. Peter Winlove Frank Vollmer Neil A. R. Gow Biosensors and Diagnostics for Fungal Detection Journal of Fungi biosensors diagnostics medical mycology fungal biomarker point-of-care devices immobilization |
| title | Biosensors and Diagnostics for Fungal Detection |
| title_full | Biosensors and Diagnostics for Fungal Detection |
| title_fullStr | Biosensors and Diagnostics for Fungal Detection |
| title_full_unstemmed | Biosensors and Diagnostics for Fungal Detection |
| title_short | Biosensors and Diagnostics for Fungal Detection |
| title_sort | biosensors and diagnostics for fungal detection |
| topic | biosensors diagnostics medical mycology fungal biomarker point-of-care devices immobilization |
| url | https://www.mdpi.com/2309-608X/6/4/349 |
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