Factors influencing medication adherence in multi-ethnic Asian patients with chronic diseases in Singapore: A qualitative study

Background: Poor medication adherence can lead to adverse health outcomes and increased healthcare costs. Although reasons for medication adherence have been widely studied, less is explored about factors affecting medication adherence for patients in non-Western healthcare setting and from Asian cu...

Full description

Bibliographic Details
Main Authors: Sungwon Yoon, Yu Heng Kwan, Wei Liang Yap, Zhui Ying Lim, Jie Kie Phang, Yu Xian Loo, Junjie Aw, Lian Leng Low
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1124297/full
_version_ 1811157752365449216
author Sungwon Yoon
Sungwon Yoon
Yu Heng Kwan
Yu Heng Kwan
Yu Heng Kwan
Yu Heng Kwan
Wei Liang Yap
Zhui Ying Lim
Jie Kie Phang
Jie Kie Phang
Yu Xian Loo
Junjie Aw
Lian Leng Low
Lian Leng Low
Lian Leng Low
Lian Leng Low
Lian Leng Low
Lian Leng Low
author_facet Sungwon Yoon
Sungwon Yoon
Yu Heng Kwan
Yu Heng Kwan
Yu Heng Kwan
Yu Heng Kwan
Wei Liang Yap
Zhui Ying Lim
Jie Kie Phang
Jie Kie Phang
Yu Xian Loo
Junjie Aw
Lian Leng Low
Lian Leng Low
Lian Leng Low
Lian Leng Low
Lian Leng Low
Lian Leng Low
author_sort Sungwon Yoon
collection DOAJ
description Background: Poor medication adherence can lead to adverse health outcomes and increased healthcare costs. Although reasons for medication adherence have been widely studied, less is explored about factors affecting medication adherence for patients in non-Western healthcare setting and from Asian cultures. This study aimed to explore cultural perspectives on factors influencing medication adherence among patients with chronic diseases in a multi-ethnic Asian healthcare setting.Methods: We conducted a qualitative study involving in-depth interviews with patients with chronic conditions purposively recruited from a community hospital in Singapore until data saturation was achieved. A total of 25 patients participated in this study. Interviews were transcribed and thematically analyzed. Themes were subsequently mapped into the World Health Organization (WHO) Framework of Medication Adherence.Results: Participants commonly perceived that sides effects (therapy-related dimension), poor understanding of medication (patient-related dimension), limited knowledge of condition (patient-related dimension), forgetfulness (patient-related dimension) and language issues within a multi-ethnic healthcare context (healthcare team and system-related dimension) as the main factors contributing to medication adherence. Importantly, medication adherence was influenced by cultural beliefs such as the notion of modern medicines as harms and fatalistic orientations towards escalation of doses and polypharmacy (patient-related dimension). Participants made various suggestions to foster adherence, including improved patient-physician communication, enhanced care coordination across providers, use of language familiar to patients, patient education and empowerment on the benefits of medication and medication adjustment.Conclusion: A wide range of factors influenced medication adherence, with therapy- and patient-related dimensions more pronounced compared to other dimensions. Findings demonstrated the importance of cultural beliefs that may influence medication adherence. Future efforts to improve medication adherence should consider a person-centered approach to foster more positive health expectations and self-efficacy on medication adherence, supplemented with routine reviews, development of pictograms and cultural competence training for healthcare professionals.
first_indexed 2024-04-10T05:12:37Z
format Article
id doaj.art-5ce5fa84bde544b0bc4f505ecfe76836
institution Directory Open Access Journal
issn 1663-9812
language English
last_indexed 2024-04-10T05:12:37Z
publishDate 2023-03-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Pharmacology
spelling doaj.art-5ce5fa84bde544b0bc4f505ecfe768362023-03-09T07:02:43ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122023-03-011410.3389/fphar.2023.11242971124297Factors influencing medication adherence in multi-ethnic Asian patients with chronic diseases in Singapore: A qualitative studySungwon Yoon0Sungwon Yoon1Yu Heng Kwan2Yu Heng Kwan3Yu Heng Kwan4Yu Heng Kwan5Wei Liang Yap6Zhui Ying Lim7Jie Kie Phang8Jie Kie Phang9Yu Xian Loo10Junjie Aw11Lian Leng Low12Lian Leng Low13Lian Leng Low14Lian Leng Low15Lian Leng Low16Lian Leng Low17Health Services and Systems Research, Duke-NUS Medical School, Singapore, SingaporeCentre for Population Health Research and Implementation, SingHealth Regional Health System, Singapore, SingaporeHealth Services and Systems Research, Duke-NUS Medical School, Singapore, SingaporeCentre for Population Health Research and Implementation, SingHealth Regional Health System, Singapore, SingaporeDepartment of Pharmacy, National University of Singapore, Singapore, SingaporeDepartment of Internal Medicine, Singapore Health Services, Singapore, SingaporeDuke-NUS Medical School, Singapore, SingaporePopulation Health and Integrated Care Office (PHICO), Singapore General Hospital, Singapore, SingaporeHealth Services and Systems Research, Duke-NUS Medical School, Singapore, SingaporeCentre for Population Health Research and Implementation, SingHealth Regional Health System, Singapore, SingaporePost-Acute and Continuing Care, Outram Community Hospital, Singapore, SingaporePost-Acute and Continuing Care, Outram Community Hospital, Singapore, SingaporeHealth Services and Systems Research, Duke-NUS Medical School, Singapore, SingaporeCentre for Population Health Research and Implementation, SingHealth Regional Health System, Singapore, SingaporePopulation Health and Integrated Care Office (PHICO), Singapore General Hospital, Singapore, SingaporePost-Acute and Continuing Care, Outram Community Hospital, Singapore, SingaporeDepartment of Family Medicine and Continuing Care, Singapore General Hospital, Singapore, SingaporeSingHealth Duke-NUS Family Medicine Academic Clinical Program, Singapore, SingaporeBackground: Poor medication adherence can lead to adverse health outcomes and increased healthcare costs. Although reasons for medication adherence have been widely studied, less is explored about factors affecting medication adherence for patients in non-Western healthcare setting and from Asian cultures. This study aimed to explore cultural perspectives on factors influencing medication adherence among patients with chronic diseases in a multi-ethnic Asian healthcare setting.Methods: We conducted a qualitative study involving in-depth interviews with patients with chronic conditions purposively recruited from a community hospital in Singapore until data saturation was achieved. A total of 25 patients participated in this study. Interviews were transcribed and thematically analyzed. Themes were subsequently mapped into the World Health Organization (WHO) Framework of Medication Adherence.Results: Participants commonly perceived that sides effects (therapy-related dimension), poor understanding of medication (patient-related dimension), limited knowledge of condition (patient-related dimension), forgetfulness (patient-related dimension) and language issues within a multi-ethnic healthcare context (healthcare team and system-related dimension) as the main factors contributing to medication adherence. Importantly, medication adherence was influenced by cultural beliefs such as the notion of modern medicines as harms and fatalistic orientations towards escalation of doses and polypharmacy (patient-related dimension). Participants made various suggestions to foster adherence, including improved patient-physician communication, enhanced care coordination across providers, use of language familiar to patients, patient education and empowerment on the benefits of medication and medication adjustment.Conclusion: A wide range of factors influenced medication adherence, with therapy- and patient-related dimensions more pronounced compared to other dimensions. Findings demonstrated the importance of cultural beliefs that may influence medication adherence. Future efforts to improve medication adherence should consider a person-centered approach to foster more positive health expectations and self-efficacy on medication adherence, supplemented with routine reviews, development of pictograms and cultural competence training for healthcare professionals.https://www.frontiersin.org/articles/10.3389/fphar.2023.1124297/fullmedication adherencechronic diseaseAsian patientsmulti-ethnic settingWHO framework
spellingShingle Sungwon Yoon
Sungwon Yoon
Yu Heng Kwan
Yu Heng Kwan
Yu Heng Kwan
Yu Heng Kwan
Wei Liang Yap
Zhui Ying Lim
Jie Kie Phang
Jie Kie Phang
Yu Xian Loo
Junjie Aw
Lian Leng Low
Lian Leng Low
Lian Leng Low
Lian Leng Low
Lian Leng Low
Lian Leng Low
Factors influencing medication adherence in multi-ethnic Asian patients with chronic diseases in Singapore: A qualitative study
Frontiers in Pharmacology
medication adherence
chronic disease
Asian patients
multi-ethnic setting
WHO framework
title Factors influencing medication adherence in multi-ethnic Asian patients with chronic diseases in Singapore: A qualitative study
title_full Factors influencing medication adherence in multi-ethnic Asian patients with chronic diseases in Singapore: A qualitative study
title_fullStr Factors influencing medication adherence in multi-ethnic Asian patients with chronic diseases in Singapore: A qualitative study
title_full_unstemmed Factors influencing medication adherence in multi-ethnic Asian patients with chronic diseases in Singapore: A qualitative study
title_short Factors influencing medication adherence in multi-ethnic Asian patients with chronic diseases in Singapore: A qualitative study
title_sort factors influencing medication adherence in multi ethnic asian patients with chronic diseases in singapore a qualitative study
topic medication adherence
chronic disease
Asian patients
multi-ethnic setting
WHO framework
url https://www.frontiersin.org/articles/10.3389/fphar.2023.1124297/full
work_keys_str_mv AT sungwonyoon factorsinfluencingmedicationadherenceinmultiethnicasianpatientswithchronicdiseasesinsingaporeaqualitativestudy
AT sungwonyoon factorsinfluencingmedicationadherenceinmultiethnicasianpatientswithchronicdiseasesinsingaporeaqualitativestudy
AT yuhengkwan factorsinfluencingmedicationadherenceinmultiethnicasianpatientswithchronicdiseasesinsingaporeaqualitativestudy
AT yuhengkwan factorsinfluencingmedicationadherenceinmultiethnicasianpatientswithchronicdiseasesinsingaporeaqualitativestudy
AT yuhengkwan factorsinfluencingmedicationadherenceinmultiethnicasianpatientswithchronicdiseasesinsingaporeaqualitativestudy
AT yuhengkwan factorsinfluencingmedicationadherenceinmultiethnicasianpatientswithchronicdiseasesinsingaporeaqualitativestudy
AT weiliangyap factorsinfluencingmedicationadherenceinmultiethnicasianpatientswithchronicdiseasesinsingaporeaqualitativestudy
AT zhuiyinglim factorsinfluencingmedicationadherenceinmultiethnicasianpatientswithchronicdiseasesinsingaporeaqualitativestudy
AT jiekiephang factorsinfluencingmedicationadherenceinmultiethnicasianpatientswithchronicdiseasesinsingaporeaqualitativestudy
AT jiekiephang factorsinfluencingmedicationadherenceinmultiethnicasianpatientswithchronicdiseasesinsingaporeaqualitativestudy
AT yuxianloo factorsinfluencingmedicationadherenceinmultiethnicasianpatientswithchronicdiseasesinsingaporeaqualitativestudy
AT junjieaw factorsinfluencingmedicationadherenceinmultiethnicasianpatientswithchronicdiseasesinsingaporeaqualitativestudy
AT lianlenglow factorsinfluencingmedicationadherenceinmultiethnicasianpatientswithchronicdiseasesinsingaporeaqualitativestudy
AT lianlenglow factorsinfluencingmedicationadherenceinmultiethnicasianpatientswithchronicdiseasesinsingaporeaqualitativestudy
AT lianlenglow factorsinfluencingmedicationadherenceinmultiethnicasianpatientswithchronicdiseasesinsingaporeaqualitativestudy
AT lianlenglow factorsinfluencingmedicationadherenceinmultiethnicasianpatientswithchronicdiseasesinsingaporeaqualitativestudy
AT lianlenglow factorsinfluencingmedicationadherenceinmultiethnicasianpatientswithchronicdiseasesinsingaporeaqualitativestudy
AT lianlenglow factorsinfluencingmedicationadherenceinmultiethnicasianpatientswithchronicdiseasesinsingaporeaqualitativestudy