Potential fluoride toxicity from oral medicaments: A review
The beneficial effects of fluoride on human oral health are well studied. There are numerous studies demonstrating that a small amount of fluoride delivered to the oral cavity decreases the prevalence of dental decay and results in stronger teeth and bones. However, ingestion of fluoride more than t...
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Format: | Article |
Language: | English |
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Mashhad University of Medical Sciences
2017-08-01
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Series: | Iranian Journal of Basic Medical Sciences |
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Online Access: | http://ijbms.mums.ac.ir/article_9104_41778d9ccb9fe6fdc55b5379a8f35463.pdf |
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author | Rizwan Ullah Muhammad Sohail Zafar Nazish Shahani |
author_facet | Rizwan Ullah Muhammad Sohail Zafar Nazish Shahani |
author_sort | Rizwan Ullah |
collection | DOAJ |
description | The beneficial effects of fluoride on human oral health are well studied. There are numerous studies demonstrating that a small amount of fluoride delivered to the oral cavity decreases the prevalence of dental decay and results in stronger teeth and bones. However, ingestion of fluoride more than the recommended limit leads to toxicity and adverse effects. In order to update our understanding of fluoride and its potential toxicity, we have described the mechanisms of fluoride metabolism, toxic effects, and management of fluoride toxicity. The main aim of this review is to highlight the potential adverse effects of fluoride overdose and poorly understood toxicity. In addition, the related clinical significance of fluoride overdose and toxicity has been discussed. |
first_indexed | 2024-04-12T15:45:25Z |
format | Article |
id | doaj.art-5ceb90491f9749f3b349e0cbc4fe23fe |
institution | Directory Open Access Journal |
issn | 2008-3866 2008-3874 |
language | English |
last_indexed | 2024-04-12T15:45:25Z |
publishDate | 2017-08-01 |
publisher | Mashhad University of Medical Sciences |
record_format | Article |
series | Iranian Journal of Basic Medical Sciences |
spelling | doaj.art-5ceb90491f9749f3b349e0cbc4fe23fe2022-12-22T03:26:41ZengMashhad University of Medical SciencesIranian Journal of Basic Medical Sciences2008-38662008-38742017-08-0120884184810.22038/ijbms.2017.91049104Potential fluoride toxicity from oral medicaments: A reviewRizwan Ullah0Muhammad Sohail Zafar1Nazish Shahani2Department of Oral Biology, Sindh Institute of Oral Health Sciences Jinnah Sindh Medical University, Karachi, PakistanDepartment of Restorative Dentistry, College of Dentistry, Taibah University, Al Madinah Al Munawwarah, Saudi Arabia|Department of Dental Materials, Islamic International Dental College, Riphah International University, Islamabad, PakistanDepartment of Oral Biology, Sindh Institute of Oral Health Sciences Jinnah Sindh Medical University, Karachi, PakistanThe beneficial effects of fluoride on human oral health are well studied. There are numerous studies demonstrating that a small amount of fluoride delivered to the oral cavity decreases the prevalence of dental decay and results in stronger teeth and bones. However, ingestion of fluoride more than the recommended limit leads to toxicity and adverse effects. In order to update our understanding of fluoride and its potential toxicity, we have described the mechanisms of fluoride metabolism, toxic effects, and management of fluoride toxicity. The main aim of this review is to highlight the potential adverse effects of fluoride overdose and poorly understood toxicity. In addition, the related clinical significance of fluoride overdose and toxicity has been discussed.http://ijbms.mums.ac.ir/article_9104_41778d9ccb9fe6fdc55b5379a8f35463.pdfFluoridationFluorideOral healthToxicityWater fluoridation |
spellingShingle | Rizwan Ullah Muhammad Sohail Zafar Nazish Shahani Potential fluoride toxicity from oral medicaments: A review Iranian Journal of Basic Medical Sciences Fluoridation Fluoride Oral health Toxicity Water fluoridation |
title | Potential fluoride toxicity from oral medicaments: A review |
title_full | Potential fluoride toxicity from oral medicaments: A review |
title_fullStr | Potential fluoride toxicity from oral medicaments: A review |
title_full_unstemmed | Potential fluoride toxicity from oral medicaments: A review |
title_short | Potential fluoride toxicity from oral medicaments: A review |
title_sort | potential fluoride toxicity from oral medicaments a review |
topic | Fluoridation Fluoride Oral health Toxicity Water fluoridation |
url | http://ijbms.mums.ac.ir/article_9104_41778d9ccb9fe6fdc55b5379a8f35463.pdf |
work_keys_str_mv | AT rizwanullah potentialfluoridetoxicityfromoralmedicamentsareview AT muhammadsohailzafar potentialfluoridetoxicityfromoralmedicamentsareview AT nazishshahani potentialfluoridetoxicityfromoralmedicamentsareview |