Experimental evaluation of Hygrophila Schulli seed extracts for antistress activity
Background: Stress is the causative factor for various diseases and disorders faced by majority of the diseased population. The seeds of Kokilākṣa Hygrophila schulli are attributed with Rasāyana properties as per the Ayurvedic literature. Considering the above, the seed extracts of H. schulli were s...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2017-01-01
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| Series: | Ancient Science of Life |
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| Online Access: | http://www.ancientscienceoflife.org/article.asp?issn=0257-7941;year=2017;volume=37;issue=1;spage=31;epage=36;aulast=Kannur |
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| author | Dayanand Kannur Srikrishna Nandanwadkar Swapnil Dhawane Smruti Phulambrikar Kishanchandra Khandelwal |
| author_facet | Dayanand Kannur Srikrishna Nandanwadkar Swapnil Dhawane Smruti Phulambrikar Kishanchandra Khandelwal |
| author_sort | Dayanand Kannur |
| collection | DOAJ |
| description | Background: Stress is the causative factor for various diseases and disorders faced by majority of the diseased population. The seeds of Kokilākṣa Hygrophila schulli are attributed with Rasāyana properties as per the Ayurvedic literature. Considering the above, the seed extracts of H. schulli were screened for antistress activity in animals. Aim: To investigate the adaptogenic activity of ethanolic and hexane extracts of Hygrophila schulli seeds using in vivo models. Materials and Methods: The ethanolic and hexane extracts of Hygrophila schulli were subjected to qualitative chemical analysis to detect the presence of various phytoconstituents. The extracts were subjected HPLC analysis. The chromatographic analysis was carried out which revealed the multicomponent and complex nature of the extracts. The seed extracts of H. schulli were screened for antistress activity using Swim Endurance test in mice and Cold-Immobilization Stress model in rats to ascertain the Adaptogenic potential. Results: HPLC analysis confirmed the presence of flavonoid Quercetin, the ethanolic and hexane extracts were found to increase the swim endurance time, both extracts lowered the elevated blood glucose, cholesterol as well as triglyceride levels in cold immobilization stress model and maintained normal homeostasis. Conclusion: Hygrophila schulli enhances the physical endurance as well as normalizes the body imbalance due to stressors. The seeds of Hygrophila schulli thus possess adaptogenic property. |
| first_indexed | 2024-12-20T03:23:18Z |
| format | Article |
| id | doaj.art-5cee4aba8d0742e6aa628fb925aeb992 |
| institution | Directory Open Access Journal |
| issn | 0257-7941 |
| language | English |
| last_indexed | 2024-12-20T03:23:18Z |
| publishDate | 2017-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Ancient Science of Life |
| spelling | doaj.art-5cee4aba8d0742e6aa628fb925aeb9922022-12-21T19:55:10ZengWolters Kluwer Medknow PublicationsAncient Science of Life0257-79412017-01-01371313610.4103/asl.ASL_191_17Experimental evaluation of Hygrophila Schulli seed extracts for antistress activityDayanand KannurSrikrishna NandanwadkarSwapnil DhawaneSmruti PhulambrikarKishanchandra KhandelwalBackground: Stress is the causative factor for various diseases and disorders faced by majority of the diseased population. The seeds of Kokilākṣa Hygrophila schulli are attributed with Rasāyana properties as per the Ayurvedic literature. Considering the above, the seed extracts of H. schulli were screened for antistress activity in animals. Aim: To investigate the adaptogenic activity of ethanolic and hexane extracts of Hygrophila schulli seeds using in vivo models. Materials and Methods: The ethanolic and hexane extracts of Hygrophila schulli were subjected to qualitative chemical analysis to detect the presence of various phytoconstituents. The extracts were subjected HPLC analysis. The chromatographic analysis was carried out which revealed the multicomponent and complex nature of the extracts. The seed extracts of H. schulli were screened for antistress activity using Swim Endurance test in mice and Cold-Immobilization Stress model in rats to ascertain the Adaptogenic potential. Results: HPLC analysis confirmed the presence of flavonoid Quercetin, the ethanolic and hexane extracts were found to increase the swim endurance time, both extracts lowered the elevated blood glucose, cholesterol as well as triglyceride levels in cold immobilization stress model and maintained normal homeostasis. Conclusion: Hygrophila schulli enhances the physical endurance as well as normalizes the body imbalance due to stressors. The seeds of Hygrophila schulli thus possess adaptogenic property.http://www.ancientscienceoflife.org/article.asp?issn=0257-7941;year=2017;volume=37;issue=1;spage=31;epage=36;aulast=KannurAdaptogenicantistresscold immobilization Hygrophila schulliswim endurancestress |
| spellingShingle | Dayanand Kannur Srikrishna Nandanwadkar Swapnil Dhawane Smruti Phulambrikar Kishanchandra Khandelwal Experimental evaluation of Hygrophila Schulli seed extracts for antistress activity Ancient Science of Life Adaptogenic antistress cold immobilization Hygrophila schulli swim endurance stress |
| title | Experimental evaluation of Hygrophila Schulli seed extracts for antistress activity |
| title_full | Experimental evaluation of Hygrophila Schulli seed extracts for antistress activity |
| title_fullStr | Experimental evaluation of Hygrophila Schulli seed extracts for antistress activity |
| title_full_unstemmed | Experimental evaluation of Hygrophila Schulli seed extracts for antistress activity |
| title_short | Experimental evaluation of Hygrophila Schulli seed extracts for antistress activity |
| title_sort | experimental evaluation of hygrophila schulli seed extracts for antistress activity |
| topic | Adaptogenic antistress cold immobilization Hygrophila schulli swim endurance stress |
| url | http://www.ancientscienceoflife.org/article.asp?issn=0257-7941;year=2017;volume=37;issue=1;spage=31;epage=36;aulast=Kannur |
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