Multimodal neuroimaging in presurgical evaluation of drug-resistant epilepsy
Intracranial EEG (icEEG) monitoring is critical in epilepsy surgical planning, but it has limitations. The advances of neuroimaging have made it possible to reveal epileptic abnormalities that could not be identified previously and improve the localization of the seizure focus and the vital cortex....
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2014-01-01
|
| Series: | NeuroImage: Clinical |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213158213001472 |
| _version_ | 1818514016092291072 |
|---|---|
| author | Jing Zhang Weifang Liu Hui Chen Hong Xia Zhen Zhou Shanshan Mei Qingzhu Liu Yunlin Li |
| author_facet | Jing Zhang Weifang Liu Hui Chen Hong Xia Zhen Zhou Shanshan Mei Qingzhu Liu Yunlin Li |
| author_sort | Jing Zhang |
| collection | DOAJ |
| description | Intracranial EEG (icEEG) monitoring is critical in epilepsy surgical planning, but it has limitations. The advances of neuroimaging have made it possible to reveal epileptic abnormalities that could not be identified previously and improve the localization of the seizure focus and the vital cortex. A frequently asked question in the field is whether non-invasive neuroimaging could replace invasive icEEG or reduce the need for icEEG in presurgical evaluation. This review considers promising neuroimaging techniques in epilepsy presurgical assessment in order to address this question. In addition, due to large variations in the accuracies of neuroimaging across epilepsy centers, multicenter neuroimaging studies are reviewed, and there is much need for randomized controlled trials (RCTs) to better reveal the utility of presurgical neuroimaging. The results of multiple studies indicate that non-invasive neuroimaging could not replace invasive icEEG in surgical planning especially in non-lesional or extratemporal lobe epilepsies, but it could reduce the need for icEEG in certain cases. With technical advances, multimodal neuroimaging may play a greater role in presurgical evaluation to reduce the costs and risks of epilepsy surgery, and provide surgical options for more patients with drug-resistant epilepsy. |
| first_indexed | 2024-12-11T00:09:29Z |
| format | Article |
| id | doaj.art-5cee5189c4b34309ab59b0413afba1db |
| institution | Directory Open Access Journal |
| issn | 2213-1582 |
| language | English |
| last_indexed | 2024-12-11T00:09:29Z |
| publishDate | 2014-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | NeuroImage: Clinical |
| spelling | doaj.art-5cee5189c4b34309ab59b0413afba1db2022-12-22T01:28:10ZengElsevierNeuroImage: Clinical2213-15822014-01-014C354410.1016/j.nicl.2013.10.017Multimodal neuroimaging in presurgical evaluation of drug-resistant epilepsyJing Zhang0Weifang Liu1Hui Chen2Hong Xia3Zhen Zhou4Shanshan Mei5Qingzhu Liu6Yunlin Li7School of Biomedical Engineering, Capital Medical University, Beijing 100069, PR ChinaSchool of Biomedical Engineering, Capital Medical University, Beijing 100069, PR ChinaSchool of Biomedical Engineering, Capital Medical University, Beijing 100069, PR ChinaSchool of Biomedical Engineering, Capital Medical University, Beijing 100069, PR ChinaSchool of Biomedical Engineering, Capital Medical University, Beijing 100069, PR ChinaDepartment of Functional Neurology and Neurosurgery, Beijing Haidian Hospital, Beijing 100080, PR ChinaDepartment of Functional Neurology and Neurosurgery, Beijing Haidian Hospital, Beijing 100080, PR ChinaDepartment of Functional Neurology and Neurosurgery, Beijing Haidian Hospital, Beijing 100080, PR ChinaIntracranial EEG (icEEG) monitoring is critical in epilepsy surgical planning, but it has limitations. The advances of neuroimaging have made it possible to reveal epileptic abnormalities that could not be identified previously and improve the localization of the seizure focus and the vital cortex. A frequently asked question in the field is whether non-invasive neuroimaging could replace invasive icEEG or reduce the need for icEEG in presurgical evaluation. This review considers promising neuroimaging techniques in epilepsy presurgical assessment in order to address this question. In addition, due to large variations in the accuracies of neuroimaging across epilepsy centers, multicenter neuroimaging studies are reviewed, and there is much need for randomized controlled trials (RCTs) to better reveal the utility of presurgical neuroimaging. The results of multiple studies indicate that non-invasive neuroimaging could not replace invasive icEEG in surgical planning especially in non-lesional or extratemporal lobe epilepsies, but it could reduce the need for icEEG in certain cases. With technical advances, multimodal neuroimaging may play a greater role in presurgical evaluation to reduce the costs and risks of epilepsy surgery, and provide surgical options for more patients with drug-resistant epilepsy.http://www.sciencedirect.com/science/article/pii/S2213158213001472Multimodal neuroimagingFocus localizationEpilepsy surgeryPresurgical evaluation |
| spellingShingle | Jing Zhang Weifang Liu Hui Chen Hong Xia Zhen Zhou Shanshan Mei Qingzhu Liu Yunlin Li Multimodal neuroimaging in presurgical evaluation of drug-resistant epilepsy NeuroImage: Clinical Multimodal neuroimaging Focus localization Epilepsy surgery Presurgical evaluation |
| title | Multimodal neuroimaging in presurgical evaluation of drug-resistant epilepsy |
| title_full | Multimodal neuroimaging in presurgical evaluation of drug-resistant epilepsy |
| title_fullStr | Multimodal neuroimaging in presurgical evaluation of drug-resistant epilepsy |
| title_full_unstemmed | Multimodal neuroimaging in presurgical evaluation of drug-resistant epilepsy |
| title_short | Multimodal neuroimaging in presurgical evaluation of drug-resistant epilepsy |
| title_sort | multimodal neuroimaging in presurgical evaluation of drug resistant epilepsy |
| topic | Multimodal neuroimaging Focus localization Epilepsy surgery Presurgical evaluation |
| url | http://www.sciencedirect.com/science/article/pii/S2213158213001472 |
| work_keys_str_mv | AT jingzhang multimodalneuroimaginginpresurgicalevaluationofdrugresistantepilepsy AT weifangliu multimodalneuroimaginginpresurgicalevaluationofdrugresistantepilepsy AT huichen multimodalneuroimaginginpresurgicalevaluationofdrugresistantepilepsy AT hongxia multimodalneuroimaginginpresurgicalevaluationofdrugresistantepilepsy AT zhenzhou multimodalneuroimaginginpresurgicalevaluationofdrugresistantepilepsy AT shanshanmei multimodalneuroimaginginpresurgicalevaluationofdrugresistantepilepsy AT qingzhuliu multimodalneuroimaginginpresurgicalevaluationofdrugresistantepilepsy AT yunlinli multimodalneuroimaginginpresurgicalevaluationofdrugresistantepilepsy |