Immune Correlates of Disseminated BCG Infection in IL12RB1-Deficient Mice

Immune Correlates of Disseminated BCG Infection in IL12RB1-Deficient Mice

Interleukin-12 receptor β1 (IL12RB1)-deficient individuals show increased susceptibilities to local or disseminated BCG infection and environmental mycobacteria infection. However, the low clinical penetrance of IL12RB1 deficiency and low recurrence rate of mycobacteria infection suggest that protec...

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Bibliographic Details
Main Authors:	Xuyang Wang, Liqiu Jia, Yang Liu, Jing Wang, Chao Qiu, Tao Li, Wenhong Zhang, Zhaoqin Zhu, Jing Wu, Yanmin Wan
Format:	Article
Language:	English
Published:	MDPI AG 2022-07-01
Series:	Vaccines
Subjects:	IL12RB1 MSMD IFN-γ BCG innate immunity adaptive immunity
Online Access:	https://www.mdpi.com/2076-393X/10/7/1147

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