Increased TRPV1 Channels and FosB Protein Expression Are Associated with Chronic Epileptic Seizures and Anxiogenic-like Behaviors in a Preclinical Model of Temporal Lobe Epilepsy

Increased TRPV1 Channels and FosB Protein Expression Are Associated with Chronic Epileptic Seizures and Anxiogenic-like Behaviors in a Preclinical Model of Temporal Lobe Epilepsy

Epilepsies are neurological disorders characterized by chronic seizures and their related neuropsychiatric comorbidities, such as anxiety. The Transient Receptor Potential Vanilloid type-1 (TRPV1) channel has been implicated in the modulation of seizures and anxiety-like behaviors in preclinical mod...

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Bibliographic Details
Main Authors: Willian Lazarini-Lopes, Gleice Kelli Silva-Cardoso, Christie Ramos Andrade Leite-Panissi, Norberto Garcia-Cairasco
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Biomedicines
Subjects:
epilepsy
anxiety
TRPV1 channels
neuronal activity
neuropsychiatric comorbidity
immunofluorescence
Online Access:https://www.mdpi.com/2227-9059/10/2/416

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