The Optimal Balance between Oncolytic Viruses and Natural Killer Cells: A Mathematical Approach

The Optimal Balance between Oncolytic Viruses and Natural Killer Cells: A Mathematical Approach

Oncolytic virotherapy (OV) is a cancer therapy utilizing lytic viruses that specifically target cancer cells for elimination. In this relatively new therapy, two contradictory observations have been made. Some studies showed that immune responses including activated natural killer (NK) cells post on...

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Bibliographic Details
Main Authors: Dongwook Kim, Dong-Hoon Shin, Chang K. Sung
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Mathematics
Subjects:
oncolytic virotherapy
NK cells
bifurcation
dynamical system
mathematical model
Online Access:https://www.mdpi.com/2227-7390/10/18/3370

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