An Engineered Prussian Blue Nanoparticles‐Based Nanoimmunotherapy Elicits Robust and Persistent Immunological Memory in a TH‐MYCN Neuroblastoma Model

An Engineered Prussian Blue Nanoparticles‐Based Nanoimmunotherapy Elicits Robust and Persistent Immunological Memory in a TH‐MYCN Neuroblastoma Model

A combination therapy using Prussian blue nanoparticles (PBNP) as photothermal therapy (PTT) agents coated with CpG oligodeoxynucleotides, an immunologic adjuvant, as a nanoimmunotherapy (CpG‐PBNP‐PTT) for neuroblastoma (NB) is described. NB driven by MYCN amplification confers high risk and correla...

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Bibliographic Details
Main Authors: Anshi Shukla, Juliana Cano-Mejia, Jaclyn Andricovich, Rachel A. Burga, Elizabeth E. Sweeney, Rohan Fernandes
Format: Article
Language:English
Published: Wiley-VCH 2021-08-01
Series:Advanced NanoBiomed Research
Subjects:
abscopal effect
CpG oligodeoxynucleotides
MYCN amplification
nanoimmunotherapy
neuroblastoma
photothermal therapy
Online Access:https://doi.org/10.1002/anbr.202100021

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