The Assessment of the Usefulness of Prenatal Magnetic Resonance Imaging in the Diagnosis of Central Nervous System Defects
Central nervous system (CNS) abnormalities cause about 40% of infant deaths in the first year of life. In case of the detection of abnormalities by ultrasound, a pregnant woman should be offered prenatal magnetic resonance imaging (pMRI). The aims of our study were: (1) to evaluate the effectiveness...
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| Format: | Article |
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MDPI AG
2021-09-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/11/9/1723 |
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| author | Magdalena Kołak Izabela Herman-Sucharska Małgorzata Radoń-Pokracka Małgorzata Stolarek Anna Horbaczewska Hubert Huras |
| author_facet | Magdalena Kołak Izabela Herman-Sucharska Małgorzata Radoń-Pokracka Małgorzata Stolarek Anna Horbaczewska Hubert Huras |
| author_sort | Magdalena Kołak |
| collection | DOAJ |
| description | Central nervous system (CNS) abnormalities cause about 40% of infant deaths in the first year of life. In case of the detection of abnormalities by ultrasound, a pregnant woman should be offered prenatal magnetic resonance imaging (pMRI). The aims of our study were: (1) to evaluate the effectiveness of pMRI in the diagnosis of selected fetal CNS defects; and (2) to assess the possibility of replacing postnatal tests with prenatal magnetic resonance. The prospective and observational study was conducted between 2014 and 2017 at the University Hospital in Krakow. Patients with suspected CNS defects of the fetus were qualified for pMRI in the third trimester of pregnancy. Sixty patients were included in the study group. Prenatal MRI was characterized by low accuracy in the diagnosis of complex brain defects. Cohen’s kappa coefficient κ = 0.21 (95% CI 0.00–0.46). No evidence was found suggesting the replacement of postnatal tests with pMRI. MRI was characterized by low consistency of diagnoses in the case of complex brain defects. The possibility of replacing postnatal studies with pMRI was not supported. |
| first_indexed | 2024-03-10T07:45:25Z |
| format | Article |
| id | doaj.art-5cfdc08bde6a4782852326a6762fd8f7 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-10T07:45:25Z |
| publishDate | 2021-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-5cfdc08bde6a4782852326a6762fd8f72023-11-22T12:41:26ZengMDPI AGDiagnostics2075-44182021-09-01119172310.3390/diagnostics11091723The Assessment of the Usefulness of Prenatal Magnetic Resonance Imaging in the Diagnosis of Central Nervous System DefectsMagdalena Kołak0Izabela Herman-Sucharska1Małgorzata Radoń-Pokracka2Małgorzata Stolarek3Anna Horbaczewska4Hubert Huras5Department of Obstetrics and Perinatology, Medical College, Jagiellonian University, 23 Kopernika Str., 31-501 Krakow, PolandDepartment of Radiology, Medical College, Jagiellonian University, 19 Kopernika Str., 31-501 Krakow, PolandDepartment of Obstetrics and Perinatology, Medical College, Jagiellonian University, 23 Kopernika Str., 31-501 Krakow, PolandFaculty of Medical Sciences and Health Sciences, Kazimierz Pułaski University of Technology and Humanities in Radom, 29 Malczewskiego Str., 26-600 Radom, PolandDepartment of Endocrynological Gynecology, Medical College, Jagiellonian University, 23 Kopernika Str., 31-501 Krakow, PolandDepartment of Obstetrics and Perinatology, Medical College, Jagiellonian University, 23 Kopernika Str., 31-501 Krakow, PolandCentral nervous system (CNS) abnormalities cause about 40% of infant deaths in the first year of life. In case of the detection of abnormalities by ultrasound, a pregnant woman should be offered prenatal magnetic resonance imaging (pMRI). The aims of our study were: (1) to evaluate the effectiveness of pMRI in the diagnosis of selected fetal CNS defects; and (2) to assess the possibility of replacing postnatal tests with prenatal magnetic resonance. The prospective and observational study was conducted between 2014 and 2017 at the University Hospital in Krakow. Patients with suspected CNS defects of the fetus were qualified for pMRI in the third trimester of pregnancy. Sixty patients were included in the study group. Prenatal MRI was characterized by low accuracy in the diagnosis of complex brain defects. Cohen’s kappa coefficient κ = 0.21 (95% CI 0.00–0.46). No evidence was found suggesting the replacement of postnatal tests with pMRI. MRI was characterized by low consistency of diagnoses in the case of complex brain defects. The possibility of replacing postnatal studies with pMRI was not supported.https://www.mdpi.com/2075-4418/11/9/1723magnetic resonancecentral nervous systemprenataldiagnosis |
| spellingShingle | Magdalena Kołak Izabela Herman-Sucharska Małgorzata Radoń-Pokracka Małgorzata Stolarek Anna Horbaczewska Hubert Huras The Assessment of the Usefulness of Prenatal Magnetic Resonance Imaging in the Diagnosis of Central Nervous System Defects Diagnostics magnetic resonance central nervous system prenatal diagnosis |
| title | The Assessment of the Usefulness of Prenatal Magnetic Resonance Imaging in the Diagnosis of Central Nervous System Defects |
| title_full | The Assessment of the Usefulness of Prenatal Magnetic Resonance Imaging in the Diagnosis of Central Nervous System Defects |
| title_fullStr | The Assessment of the Usefulness of Prenatal Magnetic Resonance Imaging in the Diagnosis of Central Nervous System Defects |
| title_full_unstemmed | The Assessment of the Usefulness of Prenatal Magnetic Resonance Imaging in the Diagnosis of Central Nervous System Defects |
| title_short | The Assessment of the Usefulness of Prenatal Magnetic Resonance Imaging in the Diagnosis of Central Nervous System Defects |
| title_sort | assessment of the usefulness of prenatal magnetic resonance imaging in the diagnosis of central nervous system defects |
| topic | magnetic resonance central nervous system prenatal diagnosis |
| url | https://www.mdpi.com/2075-4418/11/9/1723 |
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