AKAP150 Palmitoylation Regulates Synaptic Incorporation of Ca2+-Permeable AMPA Receptors to Control LTP
Summary: Ca2+-permeable AMPA-type glutamate receptors (CP-AMPARs) containing GluA1 but lacking GluA2 subunits contribute to multiple forms of synaptic plasticity, including long-term potentiation (LTP), but mechanisms regulating CP-AMPARs are poorly understood. A-kinase anchoring protein (AKAP) 150...
Main Authors: | Alicia M. Purkey, Kevin M. Woolfrey, Kevin C. Crosby, Dominik G. Stich, Wallace S. Chick, Jason Aoto, Mark L. Dell’Acqua |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2018-10-01
|
Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124718315456 |
Similar Items
-
β-Amyloid disruption of LTP/LTD balance is mediated by AKAP150-anchored PKA and Calcineurin regulation of Ca2+-permeable AMPA receptors
by: Jennifer L. Sanderson, et al.
Published: (2021-10-01) -
DHHC2 regulates fear memory formation, LTP, and AKAP150 signaling in the hippocampus
by: Meng-Die Li, et al.
Published: (2023-09-01) -
Palmitoylation of A-kinase anchoring protein 79/150 modulates its nanoscale organization, trafficking, and mobility in postsynaptic spines
by: Xiaobing Chen, et al.
Published: (2022-09-01) -
AKAP150-anchored PKA regulates synaptic transmission and plasticity, neuronal excitability and CRF neuromodulation in the mouse lateral habenula
by: Sarah C. Simmons, et al.
Published: (2024-03-01) -
S-palmitoylation regulates AMPA receptors trafficking and function: a novel insight into synaptic regulation and therapeutics
by: Jun Han, et al.
Published: (2015-01-01)