Identification and Isolation of α-Glucosidase Inhibitors from <i>Siraitia grosvenorii</i> Roots Using Bio-Affinity Ultrafiltration and Comprehensive Chromatography

Identification and Isolation of α-Glucosidase Inhibitors from <i>Siraitia grosvenorii</i> Roots Using Bio-Affinity Ultrafiltration and Comprehensive Chromatography

The discovery of bioactive compounds from medicinal plants has played a crucial role in drug discovery. In this study, a simple and efficient method utilizing affinity-based ultrafiltration (UF) coupled with high-performance liquid chromatography (HPLC) was developed for the rapid screening and targ...

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Bibliographic Details
Main Authors: Fenglai Lu, Jiayi Sun, Xiaohua Jiang, Jingru Song, Xiaojie Yan, Qinghu Teng, Dianpeng Li
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Siraitia grosvenorii</i> roots
α-glucosidase inhibitor
ultrafiltration
chemical constituents
molecular docking
Online Access:https://www.mdpi.com/1422-0067/24/12/10178

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https://www.mdpi.com/1422-0067/24/12/10178

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